Chapter 3 Flashcards
What is the basic unit that allows electrical impulses to be sent as messages in the brain?
a) Glial cells
b) Neurons
c) Histones
d) Building blocks
b)Neurons
The process whereby the brain can adapt its structure to respond to and survive in its environment is called
Neuroplasticity
The synaptic knob forms the presynaptic side of the synapse (the microscopic space between cells). What is at the other side of the synapse?
a) Axon
b) Soma
c) Vesicles
d) Dendrite
d) Dendrite
Sort below where the electrical activity travels from first to last.
Soma
Axon
Axon Hillock
Axon Terminal
Soma
Axon Hillock
Axon
Axon Terminal
If you had to assign the role of ‘doctor’, which glial cells would you choose? Select all that apply.
a) Schwann cells
b) Astrocytes
c) Microglia
d) Oligodendrocytes
b) Astrocytes
c) Microglia
They both help form the immune system of the brain.
Which of the following is a purpose of glial cells? Select all that apply.
a) Support
b) Sensing stimuli in the environment
c) Releasing neurotransmitters
d) Speeding up electrical impulses
a) Support
d) Speeding up electrical impulses
Match the type of cell with its proper location. CNS or PNS?
Oligodendrocytes
Schwann
Oligodendrocytes - CNS
Schwann - PNS
Myelin is made of protein and fat, and it is wrapped around the axons of some neurons in the brain and spinal cord by glial cells called oligodendrocytes. By creating the myelin sheath, these cells support the speedy processing of information between different areas in the central nervous system.
Schwann Cells wrap myelin around the nerves outside of the brain and spinal cord, thereby speeding up electrical impulses being sent from the brain and spinal cord to the body.
What determines the direction particles flow in solution?
a) Concentration: Low to High
b) Size
c) Positive vs Negative Charge
d) Concentration: High to Low
c) Positive vs Negative Charge
d) Concentration: High to Low
Which of the following will happen if I make the charge inside a neuron more positive?
a) The neuron will be more likely to deactivate
b) The neuron will be more likely to activate
c) The neuron will be damaged
d) The neuron will shut down
b) The neuron will be more likely to activate
Depolarisation
Depolarisation is brought about by the influx of Na+
Repolarisation
repolarisation happens because of the efflux of K+.
T/F: Neurons have a net negative charge at rest. This means that when they are active, they must have a positive charge.
True
If potassium concentrations in the extracellular space are lowered, which of the following problems could this cause within the neuron (keep in mind what you have learned about gradients and channels)?
a) Trouble maintaining resting potential
b) Trouble being stimulated
c) Trouble shutting down after activation
d) Trouble maintaining the integrity of the membrane
a) Trouble maintaining resting potential
c) Trouble shutting down after activation
When do sodium channels open?
During depolarisation
Neurons depolarise when they become electrically active. This is due to the __________.
Influx of sodium
Put the following steps in the right order.
Triggering of voltage-sensitive Na^+ channels
Small influx of Na^+
Efflux of K
Large influx of Na^+
Small influx of Na^+
Triggering of voltage-sensitive Na^+ channels
Large influx of Na^+
Efflux of K
A significant factor in creating the Action Potential is that the neuron is _____________
a) Almost always permeable to ions
b) Permeable to negative ions through leaky channels
c) Only semi-permeable to ions
d) Completely impermeable to ions
c) Only semi-permeable to ions
Axon Na^+ channels
Propagation of the action potential
Leaky channels
Maintenance of the resting potential
Lipid bilayer
Making the membrane semi-permeable
Myelin
Speeding up conduction of the electrical impulse
Which of the following do cells in your nervous system use to process information (choose all that apply)?
a) Electrical activity
b) Chemicals
c) Changes in shape of the cell
d) Colour
a) Electrical activity
b) Chemicals
If I tell you that the membrane of the neuron below is normally impermeable to ions, and you know that the movement of charged particles is how electrical impulses happen, how do we solve this problem?
a) I would break open the membrane.
b) I would make a door that can open and close.
c) I would just change the membrane to make it permeable.
d) I would make electricity happen without charged particles.
b) I would make a door that can open and close.
An excitatory neurotransmitter binding to a receptor would make the charge inside the neuron more:
a) Positive
b) Negative
c) Superpolarised
d) Neutral
a) Positive
Agonists
mimic the action of an endogenous (naturally produced by the body) neurotransmitter.
Antagonists
prevent the action of the endogenous neurotransmitter. Agonists or antagonists can be competitive (direct),
Partial agonists/antagonists.
This means that they bind to and activate the receptor with less ‘power’ than the endogenous neurotransmitter.
You are an evil villain who just happens to be masquerading as a psychiatrist. You want to increase depression in your patients. Which of the following would be most effective in your evil plan?
a) A dopamine receptor agonist
b) A norepinephrine receptor agonist
c) A partial dopamine receptor antagonist
d) A serotonin receptor antagonist
d) A serotonin receptor antagonist
When K+ ions rush out of the neuron, what happens to the charge inside the neuron?
a) The charge becomes more positive, because positive ions are leaving.
b) The charge stays neutral, because one ion is not enough to change anything.
c) The charge becomes more negative, because positive ions are leaving.
d) There is not enough information to answer the question.
c) The charge becomes more negative, because positive ions are leaving.
Sort the following steps in the process of triggering an action potential.
1) Binding of a neurotransmitter to a receptor
2) Influx of positive ions into the cell body
3) Opening of voltage gated sodium channels on the cell body
4) Opening of potassium channels