Chapter 3 Flashcards
Genotype and Phenotype
Genotype: inherited genetic material
Phenotype:Observed expression of genotype
Chromosome, DNA, and Genes
-Chromosome: contain all genetic material
-DNA: the material from which chromosomes are constructed
-Genes: A segment of a chromosome (made up of DNA)
Alleles: homozygous vs heterozygous
- 2 forms of a gene located at the same place on the chromosome
-Homo: 2 identical alleles
-Hetero: 2 different alleles
Regulator Genes
Patterns of Inheritance: Dominant-Recessive
-Under heterozygous conditions, the influence of only one allele is apparent
-Recessive gene disorders: Phenylketonuria, Cystic Fibrosis
Patterns of Inheritance: X-linked
-A recessive gene is carried on the X chromosome
-Males more likely to be affected (color blindness, hemophilia)
Patterns of Inheritance: Codominance
-Both alleles in a heterozygous combination are expressed
Patterns of Inheritance: Mutation
-Sudden, permanent change in a segment of DNA
Chromosomal & Gene Anomalies
-Errors in cell division can result in zygotes with extra or missing chromosomes or genes
-Down syndrome (Extra chromosome)
-XYY Syndrome
-Klinefelter Syndrome (XXY)
-Triple X syndrome (XXX)
-Turner syndrome (XO)
Norm of Reaction
-All the phenotypes that can theoretically result from a given genotype in relation to all the environments in which it can survive/ develop
Gene-Environment Interaction: PKU example
-Inherited vulnerability and specific environmental conditions are needed to produce a disorder
-Phenylketonuria: Defective gene on chromosome 12 (allows us to metabolize phenylalanine )
Reciprocal Gene-Environment model
-Those with a genetic predisposition for a disorder may also have a genetic tendency to create environmental risk factors that promote the disorder
Behavior Genetics: Heritability
-Extent to which variability in a particular behavior in a population can be accounted for by genetic factors
-Large population rather than individual
Behavior Genetics: Shared and Nonshared environment Factors
-Shared: what family member have in common
-Nonshared: what is distinct among family members
Behavior Genetics: Research Designs
-Study that observed nature and nurture between twins and siblings and whether they were raised together or separately