Chapter 3 #1 Flashcards

0
Q

What is the classic pattern of neural function?

A

Info flows within a neuron via electrical signals (action potentials) and passes between neurons through chemical signals (neurotransmitters)

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1
Q

Neurophysiology

A

The study of the life processes of neurons

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2
Q

Polarized

A

Exhibits a difference between the electric charge inside and outside of a cell.

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3
Q

All living cells are more negative on the inside than the outside. T or F?

A

True!

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4
Q

Ion

A

Electrically charged molecules contained in a neuron

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5
Q

Anions

A

Negatively charged ions. These are the majority of large protein ions within the cell that can’t exit.

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6
Q

Cations

A

Positively charged ions in a neuron

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7
Q

Intracellular fluid

A

Watery solution inside the neuron where ions are dissolved. Also known as cytoplasm

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8
Q

Extra cellular fluid

A

Fluid in between cells (interstitial fluid) surrounds the cell membrane and contains dissolved ion

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9
Q

Cell membrane

A

The lipid bilateral that ensheathes a cell

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10
Q

Microelectrode

A

Especially small electrode used to record electrical potentials in living cells

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11
Q

Resting potential

A

A difference in electrical potential across the membrane of a nerve cell during an inactive period

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12
Q

What is the difference in electrical potentials across a resting neuron’s membrane?

A

-50 to -80 millivolts (mV)

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13
Q

Millivolts (mV)

A

A thousandth of a volt

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14
Q

Ion channel

A

A pore in the cell membrane that permits the passage of certain ions through the membrane when the channels are open

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15
Q

Potassium ion (K+)

A

A potassium atom that carries a positive charge because it has lost one electron

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16
Q

Selective permeability

A

Property if the membrane to allow some substances to pass through but not others (K+ channels)

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17
Q

Diffusion

A

Tendency of molecules to move from areas of high concentration to lower concentration until a uniform concentration is achieved

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18
Q

Electrostatic pressure

A

The propensity of charged molecules to move, via diffusion, towards areas with the opposite charge.

19
Q

What are the two main forces that drive ions in and out of the neuron?

A

Diffusion and electrostatic pressure

20
Q

Sodium potassium pumps

A

Energetically expensive mechanism that pushes sodium ions out of a cell and potassium ions in.

21
Q

What is the ratio at which the sodium potassium pumps each ion?

A

Three Na+ for every 2 K+

22
Q

Sodium ion (Na+)

A

A sodium atom that carries a positive charge because it has lost one electron

23
Q

Equilibrium potential

A

The point at which the movement if ions across the cell membrane is balanced, as the electrostatic pressure pulling ions in one direction is offset by the diffusion force pushing them in the opposite direction

24
Q

The pump and diffusion create a high intracellular concentration of which ion?

A

K+

25
Q

The pump and diffusion create a high extracellular concentration of which ion?

A

Na+

26
Q

Hyperpolarization

A

Increase in membrane potential, the inside of the neuron becomes more negative

27
Q

Depolarization

A

Brings the membrane potential closer to zero, making the potential of the inside more like the outside

28
Q

What happens when a hyper polarizing stimulus to the membrane?

A

Passively mirrors the stimulus pulse.

29
Q

Graded response

A

The greater the stimulus the greater the response

30
Q

Local potential

A

An electrical potential that is initiated by stimulation at a specific site spreads passively across the membrane and get weaker as they spread away from the point of stimulation

31
Q

Threshold

A

The stimulus intensity that is just adequate to trigger an action potential at the axon hillock

32
Q

How far must a cell become depolarizer before it reaches the threshold?

A

Around -40 mV or so

33
Q

Action potential

A

“Spike”. Rapid reversal of the membrane potential that momentarily makes the inside of he membrane positive with respect to the outside

34
Q

Is the action potential actively or passively reproduced?

A

Actively

35
Q

All or none property

A

The amplitude of the action potential is independent to the size of the stimuli. It fires fully or not at all.

36
Q

How does the size of the stimuli effect the action potential?

A

With stronger stimuli more action potentials are produce but the size is the same

37
Q

After potential

A

The positive or negative change in membrane potential following an action potential.

38
Q

Knee jerk reflex

A

Stretching of the tendon beneath the knee leads to an upward kick of the leg

39
Q

Electroencephalogram (EEG)

A

Records gross electrical activity of the brain via large electrodes placed on the scalp

40
Q

Event related potential/ evoked potential

A

Averaged EEG recordings measuring brain responses to repeated presentations of a stimulus

41
Q

Epilepsy

A

A brain disorder marked by major sudden changes in the electrophysiological state of the brain that are referred to as seizures

42
Q

Grand mal seizure

A

Epileptic seizure in which nerve cells fire in high frequency bursts, usually accompanied by involuntary rhythmic contractions of the body

43
Q

Petit mal seizure

A

“Absence attack” seizures with spike and wave EEG and involves a loss of awareness and ability to recall surrounding events

44
Q

Complex partial seizures

A

A type of seizure that doesn’t involve entire brain and can cause a variety of abnormal behaviors

45
Q

Aura

A

The unusual sensations or premonition that may precede the beginning of an epileptic seizure.