Chapter 295 - Mechanical Ventilatory Support Flashcards
What is the primary indication for initiation of MV
Respiratory Failure
Types of respiratory failure
hypoxemic
hypercarbic
Hypoxemic respiratory failure occurs when arterial O2 saturation falls below which level despite an increased FiO2
<90%
Hypoxemic respiratory failure results from which conditions?
VQ mismatch
Shunt
Hypercarbic respiratory failure occurs if arterial CO2 values are greater than which level?
> 50 mmhg
Hypercarbic respiratory failure results from which conditions?
decrease minute ventilation
increase physiologic dead space
When respiratory failure is CHRONIC, patients are obligatorily treated with mechanical ventilation.
FALSE
only when acute is MV lifesaving
Respiratory failure with hypoxemia is the most common reason for instituting MV. This accounts for how many percent of all ventilated cases?
65%
Most common cause of hypercarbic respiratory failure?
Coma (15%)
COPD in exacerbation (13%) Neuromuscular disease (13%)
What are the primary objectives of MV?
- decrease work of breathing
2. reverse life threatening hypoxemia and acidosis
Complications of NIV?
pneumonia
tracheolaryngeal trauma
2 most frequently implemented ways of NIV
- bilevel positive airway pressure ventilation
2. pressure support ventilation
Major limitation of NIV
patient intolerance
Most important group of patients who benefit from a trial of NIV
COPD in exacerbation Respiratory acidosis (pH <7.35)
blood pH level associated with low failure rates (15-20%) and good outcomes with NIV
7.25 - 7.35
In more severely ill patients, with blood pH <7.25, the rate of NIV failure is inversely related to the severity of the respiratory acidosis; the lower the pH the higher the rate of failure
TRUE
Good clinical indicators of the therapeutic benefit of NIV
- reduction in respiratory frequency
2. decrease in the use of accessory muscles
What characterizes a conditioned gas?
warmed, oxygenated, humidified
Good choices of sedatives during intubation but can have a deleterious effect on hemodynamics in patients with depressed cardiac function or low systemic vascular resistance
Opiates and benzodiazepines
Drug used during intubation that can promote histamine release from tissue mast cells and may worsen bronchospasm
Morphine
Drug that may increase systemic arterial pressure and has been associated with hallucinatory responses
Ketamine
Contraindications for NIV
Cardiac/ respiratory arrest Severe encephalopathy Severe GI bleed Hemodynamic instability Unstable angina or MI Facial surgery or trauma Upper airway obstruction High risk aspiration inability to clear secretions
Basic goals of MV
to optimize oxygenation while avoiding ventilator induced lung injury due to overstretch and collapse/re-recruitment
(protective ventilatory strategy)