Chapter 2.8 ~ Genetic Mutations Flashcards
Mutagen
A mutagen is an agent or factor that is able to influence or increase rate of mutations in DNA
The factor or trigger of a mutation
Spontaneous Mutation
When the cause of a mutation can’t be identified
Induced Mutation
When the cause of a mutation can be identified
Mutagenic Agents
Mutagenic agents are the things that can cause or contribute to the development of mutations in our DNA
Radiation: Ultraviolet radiation, nuclear radiation, x-rays
Chemicals: Formalin, benzene
Ozone Layer: When we thin the ozone layer we become increasingly exposed to ultraviolet radiation
Point Muatations
Point mutations are mutations in a specific part of the DNA sequence that have the ability of causing a substitution, deletion or insertion mutation.
Insertion Mutation
The type of mutation when the nucleotide is inserted into to original nucleotide sequence of DNA
Deletion Mutation
The type of mutation when one of the nucleotides in the DNA is deleted from the DNA sequence
Substitution Mutation
The type of mutation when one of the nucleotides are substituted for a different nucleotide within the DNA sequence
Sickle-Cell Anaemia
Suckle-cell anaemia is a disease associated with mutations the the genetic code for one of the polypeptides that make haemoglobin in the red blood cells. This is because the Adenine-A base is substituted by the Thymine-T base
When deformed red blood cells can bunch together and block blood vessels
Mutation
A mutation is a fault or change in the DNA sequence ~ at the chromosome or gene level