Chapter 28 Flashcards
What causes pH changes to a solution?
Addition of an acid or a base
Is the pH of intracellular versus extracellular compartments similar or different?
Quite different, indeed, good sir.
What minimizes the effects of rapid pH changes (when you add acid or base)?
Buffers
According to the Henderson-Hasselbach equation, pH depends on?
The ratio of CO2 / HCO3-
If you double pCO2, how will the pH be affected? How does it affect HCO3- concentration?
It will drop by 0.3 units (making it more acidic). It does not change HCO3- concentration.
If you double HCO3-, how will the pH be affected?
It will rise by 0.3 units (making it more basic).
What does the Davenport diagram tell you?
A graph that tells you the changes in acid-base balances/disruptions in the blood.
The amount of HCO3- formed or used in respiratory pH disturbances increases with what variable?
NON-HCO3- buffering power
If you have constant pCO2, but remove acid or base, what type of disturbance will you have?
Metabolic (HCO3-) disturbance
What can compensate for a respiratory disturbance?
Metabolic change
What can compensate for a metabolic disturbance?
Respiratory change
What regulates the pH inside of cells?
Ion channels
Is the H+/K+ exchanger channel a direct exchange?
No, it is actually indirectly connected.
If you see changes in intracellular pH, you can expect?
Changes in extracellular pH
If you see changes in extracellular pH, you can expect?
Changes in intracellular pH
