Chapter 26 Upper GI tract Flashcards
Clinical symptoms associated with GERD
Dental Corrosion
Dysphagia
Heartburn (pyrosis)
Odynophagia (painful swallowing)
Regurgitation
Noncardiac chest pain
Extraesophageal symptoms
Odynophagia
Painful swallowing
Dysphagia
Difficulty initiating a swallow
Barrett’s esophagus
Precancerous condition in which normal squamous epithelium of the esophagus is replaced by an abnormal columnar-lined epithelium known as intestinal metaplasia
When acid reflux occurs with a hiatal hernia the gastric contents remain ___
above the hiatus longer than normal
Type I hernia
Sliding hiatal hernia: most common type; gastroesophageal junction is pushed above the diaphragm, causing a symmetric herniation of the proximal stomach
Type 2 hernia
True paraoesophageal hernia: fundus slides upward and moves above the gastroesophageal junction
Type 3: mixed paraesophageal hernia
Combined sliding and paraoesophageal herniation
Type 4
Complex Paraoesophageal hernia
-less common form; intrathoracic hernation of other organs such as colon and small bowel
Patients with type 3 hernia may present with severe
chest pain, retching, vomiting, hematemesis
Hematemesis
vomiting of blood
Aim in acid suppression therapy is to raise the gastric pH above ___ during periods when reflux is most likely to occur
4
What do proton pump inhibitors do
decrease acid production by the gastric parietal cell have been associated wtih superior healing rates and decreased relapses
Mild forms of reflux are managed by
H2 receptor
antagonists
and antacids
What do H2 blockers do
blocks action of histamine on parietal cells, decreasing the production of acid