Chapter 26: Drugs Affecting Blood Pressure Flashcards

1
Q

Classification of Catopril

A

Angiotension-Converting Enzyme Inhibitors

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2
Q

Angiotension Converting Enzyme Inhibitor

A

Catopril

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3
Q

Indications of Catopril

A

HTN, CHF, diabetic neuropathy, left ventricular dysfunction

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4
Q

Medication used for HTN, CHF, diabetic neuropathy, left ventricular dysfunction

A

Catopril

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5
Q

MOA of Catopril

A

Inhibits the ACE needed to change angiotensin I to angiotensin II

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6
Q

active form of angiotensin

A

angiotensin II

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7
Q

Works by inhibiting the conversion of angiotensin I to angiotensin II

A

Catopril

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8
Q

Adverse effects include persistent nonproductive cough, angioedema, rash, hypotension, neutropenia, dyspnea

A

Catopril

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9
Q

Catopril’s adverse effects

A

persistent nonproductive cough, angioedema, rash, hypotension, neutropenia, dyspnea

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10
Q

Contraindications of Catopril

A

Hypersensitivity & 2nd/3rd trimester of pregnancy

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11
Q

Vasodilation can cause:

A

decrease in BP

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12
Q

Which drug should be administered 1 hour before meals?

A

Catopril

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13
Q

Catopril’s absorption is decreased with:

A

food

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14
Q

When taking Catopril, the blood tests should test for:

A

hyperkalemia, hyponatremia, neutropenia, proteinuria in urine

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15
Q

hyperkalemia, hyponatremia, neutropenia, proteinuria in urine should be monitored for patients taking this drug:

A

Catopril

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16
Q

Mechanism results in a decrease in peripheral arterial resistance and sodium/water retention

A

Catopril

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17
Q

Angiotensin II Receptor Blocker:

A

Losartan

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18
Q

Indications include HTN, diabetic neuropathy, left ventricular dysfunction

A

Losartan

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19
Q

Losartan is used in patients with:

A

HTN, diabetic neuropathy, left ventricular dysfunction

20
Q

Alpha 2 agonist drug

A

Clonidine

21
Q

secondary anti-hypertensive medication administered PO, IV or transdermal

A

Clonidine

22
Q

Secondary anti-hypertensive medication that does not affect kidney blood flow or GFR

A

Clonidine

23
Q

Clonidine patch should be changed every ___ days

A

7

24
Q

Drug that selectively blocks the binding of angiotensin II to the angiotensin I receptors in tissues

A

Losartan

25
Q

Losartan MOA

A

selectively blocks the binding of angiotensin II to the angiotensin I receptors in tissues

26
Q

Adverse Effects of Losartan

A

Hypotension, diarrhea, asthenia, dizziness, fatigue

27
Q

Adverse effects include Hypotension, diarrhea, asthenia, dizziness, fatigue

A

Losartan

28
Q

Only contraindication is hypersensitivity

A

Losartan

29
Q

Losartan’s contraindications

A

hypersensitivity

30
Q

Interacts with lithium, flucanazole, indomethacin, rifampin and grapefruit juice

A

Losartan

31
Q

Losartan interacts with:

A

lithium, flucanazole, indomethacin, rifampin and grapefruit juice

32
Q

Grapefruit juice ____ metabolism of Losartan

A

decreases

33
Q

Levels that should be monitored during taking Losartan

A

creatinine, BUN, hemoglobin, hematocrit

34
Q

Creatinine, BUN, hemoglobin & hematocrit levels should be monitored in patients taking:

A

Losartan

35
Q

Classification of Eplerenone

A

Selective aldosterone blocker

36
Q

Selective aldosterone blocker:

A

Eplerenone

37
Q

Indication for Eplerenone

A

HTN

38
Q

MOA of Eplerenone

A

binds selectively to the mineralocorticoid receptors, blocking aldosterone from binding

39
Q

Works by binding selectively to the mineralocorticoid receptors, blocking aldosterone from binding to receptors

A

Eplerenone

40
Q

Adverse Effects include hyperkalemia, diarrhea, albuminuria, gynecomastia, abnormal vaginal bleeding, and hypercholesterolemia

A

Eplerenone

41
Q

Adverse effects of Eplerenone

A

hyperkalemia, diarrhea, albuminuria, gynecomastia, abnormal vaginal bleeding, and hypercholesterolemia

42
Q

Normal range of potassium

A

3.5-5 mEg/L

43
Q

Contraindications of Eplerenone

A

Potassium over 5.5 mEg/L, creatinine > 2 mg/dL

44
Q

salt substitutes are ___ based

A

potassium

45
Q

statins may cause:

A

severe leg aching pains