Chapter 24 - Endocrine System and Pathologies Flashcards
nervous and endocrine system can be referred as
neuroendocrine system
study of the endocrine system
endocrinology
secrete hormones directly into the bloodstream and are ductless glands
endocrine glands
secrete the products into ducts that open to body cavities, center of a hollow organ, or onto the surface of the body
exocrine glands
hypothalamus, pituitary gland, thyroid gland, parathyroid gland, adrenal gland, pancreas, ovaries, testes –> what type of glands of the endocrine system
endocrine glands
sudoferous glands, sebaceous glands, salivary glands –> what type of glands of the endocrine system?
exocrine glands
hormone production/secretion, metabolism regulation, stress adaptation, chemical composition/fluid volume regulation, and reproductive process regulation –> functions of what system?
endocrine system
chemical messengers that regulate physiologic activity of other cells
hormones
possess receptors for the corresponding hormone
target cells
stimulates the adrenal cortex to secrete hormones, especially cortisol
which hormone?
which gland?
adrenocorticotropic hormone (ACTH)
anterior pituitary
maintains sodium levels
which hormone?
which gland?
aldosterone
adrenal cortex
decreases urine production and raises BP
which hormone?
which gland?
antidiuretic hormone (ADH)
posterior pituitary
decreases blood calcium levels
which hormone?
which gland?
calcitonin (CT)
thyroid
helps ensure glucose, lipids, and amino acids are available for energy during times of stress
which hormone?
which gland?
cortisol (hydrocortisone)
adrenal cortex
enhances and prolongs sympathetic arousal
which hormone?
which gland?
epinephrine
adrenal medulla
development of female secondary sex characteristics
which hormone?
which gland?
estrogens
ovaries
females - stimulates estrogen production and ovarian follicle development
males - stimulates sperm production
which hormone?
which gland?
follicle-stimulating hormone (FSH)
anterior pituitary
increases blood glucose levels
which hormone?
which gland?
glucagon
pancreas (alpha cells)
stimulates protein synthesis for muscle and bone growth, maintenance, and repair
which hormone?
which gland?
growth hormone (GH)
anterior pituitary
decreases blood glucose levels
which hormone?
which gland?
insulin
pancreas (beta cells)
females - stimulates the release of estrogens and progesterone, ovulation, and development of the corpus luteum
males - stimulates testosterone production
which hormone?
which gland?
luteinizing hormone (LH)
anterior pituitary
increases skin pigmentation
which hormone?
which gland?
melanocyte-stimulating hormone (MSH)
intermediate pituitary
controls biorhythms or body’s 24-hour cycle
which hormone?
which gland?
melatonin
pineal
enhances and prolongs sympathetic arousal
which hormone?
which gland?
norepinephrine
adrenal medulla
stimulates uterine contractions and milk expression from mammary glands
which hormone?
which gland?
oxytocin
posterior pituitary
increases blood calcium levels
parathyroid hormone
parathryoids
maintains the uterine lining for implantation and pregnancy
progesterone
ovaries and placenta
stimulates milk production from mammary glands
prolactin
anterior pituitary
regulates metabolism
T3 + T4
thyroid
promotes male secondary sex characteristics, libido, and sperm production
testosterone
testes
stimulates T-cell maturation
thymopoietin and thymosin
thymus
stimulates the thyroid to synthesize and secrete its hormones
thyroid-stimulating hormone (TSH)
anterior pituitary
local hormones produced by many tissues and act on nearby cells
prostaglandins
response of an endocrine gland to a stimulus that moves hormone levels in the opposite (negative) direction
negative feedback
hormonal release from another endocrine gland
hormonal regulation
hormones that stimulate the activity of other endocrine glands
tropic hormones
hormone release stimulated by nerve impulses
neural regulation
located in diencephalon and secretes that stimulate or inhibit the release of pituitary hormones
hypothalamus
located in the diencephalon region and lies in the sella turcica of the sphenoid bone
pituitary gland
a stalk like structure that extends from the hypothalamus
infundibulum
allows hypothalamic hormones to travel directly to the anterior pituitary without traveling through the systemic circuit of blood flow
anterior lobe or adenohypophysis
how is the anterior lobe connected to the hypothalamus?
hypophyseal portal system
communicates with the hypothalamus by nerve impulses and regulates hormonal activity
posterior lobe = neurohypophysis
stimulates the adrenal cortex to secrete its hormones, especially cortisol
which hormone?
which gland?
adrenocorticotropic hormone (ACTH)
anterior pituitary
stimulates protein synthesis for muscle and bone growth, maintenance, and repair
which hormone?
which gland?
growth hormone (GH)
anterior pituitary
stimulates the thyroid gland to secrete its hormones, especially thyroxine
which hormone?
which gland?
thyroid-stimulating hormone (TSH)
anterior pituitary
females –> stimulates estrogen production and development of ovarian follicles
males –> stimulates testosterone production and sperm production in the testes
which hormone?
which gland?
follicle-stimulating hormone (FSH)
anterior pituitary
females –> stimulates the release of estrogens and progesterone ovulation, and development of the corpus luteum within the ovaries
males –> stimulates testosterone production within the testes
which hormone?
which gland?
luteinizing hormone (LH)
anterior pituitary
FSH and LH are collectively called ____?
gonadotropins
promotes lactation or milk production in the mammary glands located in the breasts
which hormone?
which gland?
prolactin
anterior pituitary
increases melanin production and hyperpigmentation
which hormone?
which gland?
melanocyte-stimulating hormone
anterior pituitary
decreases urine production by stimulating the kidneys to absorb more water
which hormone?
which gland?
antidiuretic hormone (ADH)
posterior pituitary
stimulates uterine contractions in pregnancy, labor, and delivery
which hormone?
which gland?
oxytocin (OT)
posterior pituitary
small pine nut-shaped structure located behind the pituitary gland between the two cerebral hemispheres int he diencephalon region
pineal gland
regulate other hormones and maintain the body’s circadian rhythm
which hormone?
which gland?
melatonin
located inferior to the larynx and anterolateral to the trachea
thyroid
how is the two lobes of the thyroid connected by?
isthmus
regulate metabolism, growth, and development
which hormone?
which gland?
T3 and T4
thyroid gland
T3 and T4 collectively called ___?
thyroid hormones (TH)
decreases blood calcium levels by stimulating osteoblastic activity
which hormone?
which gland?
calcitonin (CT)
thyroid hormones
located on the posterolateral surfaces of the thyroid lobes
parathyroids
hormones that increase blood calcium levels by stimulating osteoclastic activity
parathyroid hormone (PTH)
located superior to each kidney
adrenals
outer region of the adrenal glands
adrenal cortex
which zone of the adrenal cortex produces mineralocorticoids
outer zone
which zone of the adrenal cortex produces glucocorticoids
middle zone
which zone of the adrenal cortex produces gonadocorticoids
inner zone
hormone that activates antistress and anti-inflammatory pathways
cortisol
hormone that stabilizes blood pressure, conserves sodium, excretes potassium, and increases water retention
aldosterone
the inner region of the adrenal gland
adrenal medulla
2 types of medullary hormones
epinephrine and norepinephrine
epinephrine and norepinephrine are called ____?
neurohormones
enhances and prolongs the physiologic effects of stress
epinephrine and norepinephrine
specialized cells secreted by endocrine functions
pancreatic islets or islets of Langerhans
3 types of pancreatic cells
alpha
beta
delta
pancreatic cells that secrete glucagon
alpha cells
pancreatic cells that secrete insulin
beta cells
pancreatic cells that secrete somatostatin and pancreatic polypeptides
delta cells
hormone that increases blood glucose levels by stimulating the releases of glycogen from the liver
glucagon
hormone that decreases blood glucose levels by stimulating liver, skeletal muscle, and fat cells to absorb glucose from the blood
insulin
almond-shaped glands located in the abdominopelvic region of the female body
ovaries
secrete progesterone and estrogen
ovaries
hormone that facilitates sexual reproduction and childbirth
relaxin
hormone that suppresses the secretion of FSH by the anterior pituitary after ovulation
inhibin
hormone that is responsible for development of female secondary sex characteristics
estrogen
a pregnancy-promoting hormone that maintains the endometrium and inhibits uterine contractions
progesterone
oval glands located in the male scrotum
testes
scattered between testicular tubules
interstitial cells of Leydig
main testicular hormone
testosterone
hormone that stimulates sperm production and is the responsible for development of male secondary sex characteristics
testosterone
stimulates the production of RBCs in bone marrow
which hormone?
which organ?
erythropoietin (EPO)
kidneys
increases blood pressure by restoring pressure needed to filter blood
which hormone?
which organ?
resin
kidneys
stimulates the development of T cell
which hormone?
which organ?
thymosin
thymus
stimulates lymphocyte production (B cells and T cells differentiation)
which hormone?
which organ?
thymopoietin
thymus
donut-shaped gland that lies beneath the male urinary bladder and surrounds the urethra
prostate
flattened organ located in the pregnant uterus that secretes estrogens and progesterone
placenta
indicates pregnancy and may have an anti-antibody effect by decreasing lymphocyte activity
which hormone?
which organ?
human chorionic gonadotropin (HCG)
placenta
promote growth of the mammary glands within the breasts in preparation for lactation
which hormone?
where is it located?
placental lactogens
placenta
facilitates relaxation of the uterine wall to reduce the risk of this hormone to help the cervix relax and dilate
which hormone?
where is it located?
relaxin
placenta
initiates the secretion of gastic juices
which hormone?
where is it located?
gastrin
GI mucosa
stimulates bile and pancreatic enzyme emissions into the small intestines
which hormone?
where is it located?
cholecystokinin
GI mucosa
stimulates pancreas to secrete an alkaline liquid that neutralizes acidic chyme
which hormone?
where is it located?
secretin
GI mucosa
stimulates appetite and known as the “hunger hormone”
which hormone?
where is it located?
ghrelin
GI mucosa
inhibits gastric secretion and potentials the release of insulin from pancreatic beta cells in response to elevated blood glucose levels
which hormone?
where is it located?
gastric inhibitory polypeptide
GI mucosa
fat cells
adipocytes
plays in metabolism and energy regulation by inhibiting hunger
which hormone?
produced by?
leptin
adipocytes
increases blood sugar levels by causing body tissues less sensitive to insulin
which hormone?
produced by?
resistin
adipocytes
when the pressure-sensitive receptors in the atrium become overstretched, a hormone triggers the kidneys to increase urine production and decrease blood pressure.
which hormone?
which organ?
atrial natriuretic hormone (ANH)
heart
group of diseases characterized by chronic elevated blood glucose levels and disturbances in protein, fat, and carbohydrate metabolism
diabetes mellitus
pancreatic beta cells are damaged or destroyed, which creates a lack of insulin
diabetes mellitus type 1
pancreatic beta cells produce insulin but the cells are resistant to it
diabetes mellitus type 2
an enlargement of the thyroid gland that may occur in puberty or during pregnancy
goiter
how should you massage individuals with goiter
avoid pressure over the anterior neck
underactive thyroid gland leading to a thyroid hormone deficiency
Hashimoto disease
how should you massage individuals with Hashimoto disease?
avoid pressure over anterior neck
frail clients –> fewer changes in body positions and less pressure and slower speed
robust clients –> no change
use emollient lubricant for dry skin