Chapter 24 Flashcards

1
Q

What are the functions of the renal system

A

regulate water, ECF ions, acid base balance, remove waste toxins and drugs, hormone production

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2
Q

What hormones does the renal system makes

A

Renin and Erythropoietin

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3
Q

What does renin do

A

maintain sodium potassium levels

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4
Q

What are the two layers of the kidney

A

the cortex and medulla

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5
Q

What is the glomerulus

A

where filtrate is formed

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6
Q

What is the function of podocytes

A

form filtration barrier

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7
Q

The three major parts of the renal tubule are

A

the proximal convoluted tubule, nephron loop, and distal convoluted tubule

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8
Q

What does the proximal convoluted tubule reabsorb

A

amino acids, glucose and sodium

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9
Q

What does the proximal convoluted tubule secrete

A

metabolic wastes and drugs

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10
Q

What does the descending segment reabsorb

A

water

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11
Q

What does the ascending segment reabsorb

A

sodium and chloride

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12
Q

Blood is at how many osmoles

A

300 miliosmoles

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13
Q

What does the distal convoluted tubule reabsorb

A

water and urea H ions and bicarbonate

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14
Q

What does the distal convoluted tubule secrete

A

Hydrogen ions, bicarbonate

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15
Q

The descending loop is ____ and permeable to _____

A

thin, water

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16
Q

Does the distal convoluted tubule have lots of microvilli

17
Q

What is the function of the distal convoluted tubule

A

regulate ECF and electrolytes

18
Q

What do principal cells do

A

sodium resorption

19
Q

What do intercalated cells do

A

acid base homeostasis

20
Q

What are the three pressures involved in Net Filtration Pressure

A

glomerular hydrostatic, glomerular osmotic, and capsular hydrostatic

21
Q

What is the vasa recta

A

parallel to the loops of henle

22
Q

What are JG cells

A

enlarged smooth muscle cells of arterioles

23
Q

What do JG cells do

A

release renin

24
Q

What are the macula densa

A

salt sensors that generate paracrine signals

25
What are the three processes involved in urine production
filtration, reabsorption, and secretion
26
What are the layers of the filtration membrane
capillary endothelial, glomerular basement membrane, podocyte filtration slit membrane
27
What can not go through glomerular filtration normally
plasma proteins and RBCs
28
What percent drop in glomerular pressure will stop filtration
15
29
Would a drop in systemic blood pressure stimulate renin release
yes
30
would a slow flowing renal filtrate stimulate renin release
yes
31
would an increase in stretch of afferent arterioles stimulate renin release
no
32
would the sympathetic nervous system stimulation stimulate the renin release
yes
33
would low filtrate osmolarity stimulate renin release
yes
34
What is osmolality
solute particles in one liter of water, reflects ability to cause osmosis
35
What is the concentration of fluid entering the PCT
300 mOsm
36
What is the concentration of fluid in the medulla/ at the bottom of loop of henle
1200 mOsm
37
The only nephrons involved in the concurrent mechanism are the
juxtramedullar nephrons JGs
38
If you drink water then urine will be
dilute
39
When not well hydrated body secretes what and causes what
ADH, increases number of aquaporins in collecting duct to allow for more water resorption