Chapter 24 Flashcards

1
Q

What are the functions of the renal system

A

regulate water, ECF ions, acid base balance, remove waste toxins and drugs, hormone production

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2
Q

What hormones does the renal system makes

A

Renin and Erythropoietin

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3
Q

What does renin do

A

maintain sodium potassium levels

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4
Q

What are the two layers of the kidney

A

the cortex and medulla

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5
Q

What is the glomerulus

A

where filtrate is formed

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6
Q

What is the function of podocytes

A

form filtration barrier

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7
Q

The three major parts of the renal tubule are

A

the proximal convoluted tubule, nephron loop, and distal convoluted tubule

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8
Q

What does the proximal convoluted tubule reabsorb

A

amino acids, glucose and sodium

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9
Q

What does the proximal convoluted tubule secrete

A

metabolic wastes and drugs

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10
Q

What does the descending segment reabsorb

A

water

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11
Q

What does the ascending segment reabsorb

A

sodium and chloride

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12
Q

Blood is at how many osmoles

A

300 miliosmoles

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13
Q

What does the distal convoluted tubule reabsorb

A

water and urea H ions and bicarbonate

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14
Q

What does the distal convoluted tubule secrete

A

Hydrogen ions, bicarbonate

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15
Q

The descending loop is ____ and permeable to _____

A

thin, water

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16
Q

Does the distal convoluted tubule have lots of microvilli

A

no

17
Q

What is the function of the distal convoluted tubule

A

regulate ECF and electrolytes

18
Q

What do principal cells do

A

sodium resorption

19
Q

What do intercalated cells do

A

acid base homeostasis

20
Q

What are the three pressures involved in Net Filtration Pressure

A

glomerular hydrostatic, glomerular osmotic, and capsular hydrostatic

21
Q

What is the vasa recta

A

parallel to the loops of henle

22
Q

What are JG cells

A

enlarged smooth muscle cells of arterioles

23
Q

What do JG cells do

A

release renin

24
Q

What are the macula densa

A

salt sensors that generate paracrine signals

25
Q

What are the three processes involved in urine production

A

filtration, reabsorption, and secretion

26
Q

What are the layers of the filtration membrane

A

capillary endothelial, glomerular basement membrane, podocyte filtration slit membrane

27
Q

What can not go through glomerular filtration normally

A

plasma proteins and RBCs

28
Q

What percent drop in glomerular pressure will stop filtration

A

15

29
Q

Would a drop in systemic blood pressure stimulate renin release

A

yes

30
Q

would a slow flowing renal filtrate stimulate renin release

A

yes

31
Q

would an increase in stretch of afferent arterioles stimulate renin release

A

no

32
Q

would the sympathetic nervous system stimulation stimulate the renin release

A

yes

33
Q

would low filtrate osmolarity stimulate renin release

A

yes

34
Q

What is osmolality

A

solute particles in one liter of water, reflects ability to cause osmosis

35
Q

What is the concentration of fluid entering the PCT

A

300 mOsm

36
Q

What is the concentration of fluid in the medulla/ at the bottom of loop of henle

A

1200 mOsm

37
Q

The only nephrons involved in the concurrent mechanism are the

A

juxtramedullar nephrons JGs

38
Q

If you drink water then urine will be

A

dilute

39
Q

When not well hydrated body secretes what and causes what

A

ADH, increases number of aquaporins in collecting duct to allow for more water resorption