Chapter 23 (Fatty Acid Catabolism) Flashcards
___ is the most efficient was of storing metabolic energy
Triacylglycerols (adipose tissue) (TAG)
The more reduced a TAG is:
the more energy that is released when it is oxidized into CO2
FA are ___ meaning they do not have to be:
hydrophobic
hydrated so they can be packed tightly in the adipose tissue
Poor diets are high in ___ and ___
carbohydrates and fats
___ emulsify dietary fats in the ____
Bile salts
small intestine
Bile salts are good emulslifiers because:
they have both a hydrophobic and hydrophilic face
have a glycine tail
___ cleaves off TAG at the C#___ and C#___ positions, these are then absorbed by the ___
Lipase
1 - 3
small intestine
Chylomicrons
transport dietary fats to tissues
this occurs in the mucosal cell
When there is a low concentration of Glu ___ is released
glucagon/epinephrine
When we fast we dont use:
circulating blood glucose
Serum albumin
has 3 FA binding sites for transportation to tissues
The ___ absorbs most FAs via serum albumin because:
liver
the liver is doing gluconeogenesis
Only the ___ has Glycerol Kinase
liver
___ is the most efficient precursor for gluconeogenesis
Glycerol
___ cannot be recycled in the adipose tissue because it does not contain ___
Glycerol Glycerol Kinase (only in the liver)
Priming a FA requires (#) ATP
2
FA are primed via the enzyme ___
Fatty Acyl CoA Synthetase
___ carries fatty acyl groups across the inner mitochondrial membrane
Carnitine
SCFA = directly
LCFA = converted to acyl-carnitines
Beta-Oxidation occurs in:
the matrix of the mitochondria
The strategy of Beta-Oxidation is to create:
a carbonyl on the Beta-Carbon
The first three reaction of Beta-Oxidation are analogous to:
Succinate Dehydrogenase, Fumarase, and Malate Dehydrogenase
The fourth step of Beta-Oxidation is a ___ reaction
Claisen condensation
