Chapter 22 : Progressive Neurodegenerative Disorders

Question 1

plaques

Answer 1

scar tissue formation that reduces the axons’ ability to conduct impulses

Question 2

benign

Answer 2

person experiences one or two episodes of neurological deficits with no residual impairments

Question 3

relapsing-remitting nonprogressive

Answer 3

the person returns to the previous level of function after each exacerbation with no residual deficits

Question 4

relapsing-remitting progressive

Answer 4

a person has some residual impairment with each remission unpredictable with varied patterns of exacerbation and remission

Question 5

primary progressive

Answer 5

a steady decline in function without remissions and exacerbations

Question 6

dopamine

Answer 6

a neurotransmitter, a decrease causes deficits in the speed and quality of motor movements, postural stability, cognitive skill and effective expression

Question 7

Lewy body pathology

Answer 7

a process in which proteins abnormally fold and form intracellular inclusions within the cell body and neurons

Question 8

tremor dominant PD

Answer 8

an absence of other motor symptoms and tremors

Question 9

nontremor-dominant PD

Answer 9

akinetic-rigid syndrome and postural instability gait disorder

Question 10

preclinical period

Answer 10

when neurons have begun to degenerate but no symptoms are yet evident

Question 11

prodromal period

Answer 11

can last months or even years, generalized symptoms such as depression, anxiety, constipation, REM, behavior disorder and fatigue

Question 12

symptomatic period

Answer 12

wen class motor PD symptoms are evident followed by progressive nonmotor symptoms