chapter 21 pt 2 Flashcards
consists of sinuses gorged with concentrated erythrocytes;
red pulp
which consists of lymphocytes and macrophages aggregated like sleeves along small branches of the splenic artery
white pulp
innate type of immunity
non specific
adaptive type of immunity
specific
physical barriers
skin, hair, mucosa
chemical barriers
sweat, tears, enzyme, acid, urine
infects a cell, interferon, healthy neighboring cells
viral
are plasma proteins that bind to carbohydrates.
lectins
a lectin binds to certain sugars of a microbial cell surface and sets off yet another reaction cascade leading to C3b production.
lectin pathway,
When certain cells (especially leukocytes) are infected with viruses, they secrete proteins called
interferons
requires an antibody molecule to get it started;
classical pathway
is a group of 30 or more globu- lins that make powerful contributions to both nonspecific resistance and specific immunity
The complement system
“dying words” that alert neighboring cells and protect them from becoming infected.
interferons
C3a stimulates mast cells and baso- phils to secrete histamine and other inflammatory chemicals. It also activates and attracts neutrophils and macrophages, the two key cellular agents of pathogen destruction in inflammation.
Inflammation.
Bacteria, viruses, and other pathogens are phagocytized and digested by neutrophils and macrophages. However, those phagocytes cannot eas- ily internalize “naked” microorganisms.
phagocytosis