Chapter 21 - Disease Igs Flashcards

1
Q

low IgG, IgA
Normal/Low IgM

recurrent bacterial infection

A

Common Variable Immune Deficiency

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2
Q

low IgA

Normal IgG and IgM

A

IgA Deficiency

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3
Q

High IgM

low IgA, IgA

A

HIGM, CD40L males and CD40 females deficiency

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4
Q

low IgG/IgA

IgM can be normal

A

Transient Hypogammaglobulinemia of infacny

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5
Q

low IgM, IgG Normal

IgA and IgE elevated

A

Wiskott-Aldrich Syndrome

recurring infection by encapsulated bacteria

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6
Q

No T, B, NK cells

A

ADA

opportunistic fungal infections, autosomal recessive

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7
Q

No T and NK cells

normal # B cells

A

Jak3, IL-2 receptor signaling defect

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8
Q

No T or NK cells
Normal # B cells
most common form of SCID

A

Gamma chain deficiency, no functional B cells

males only, x-linked

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9
Q

hypocalcemia, T-cell deficiency

A

DGS

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10
Q

recurring viral infections

TAP1 glitched

A

MHC Class I deficiency

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11
Q

No NK activity, albinism

A

Chedaki-Higashi Syndrome

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12
Q

x-linked recessive, anemia

A

G6PD Deficiency

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13
Q

delayed detachment of umbilical cord

A

Leukocyte Adhesion Deficiency

LFA-1 defect

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14
Q

Neisseria infection

A

Alt. pathway defect (factor D and Properdin)

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15
Q

Neisseria in Japan

A

C9 deficiency

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16
Q

Hereditary angioedema

A

C1 inhibitor

17
Q

low/absent IgG, IgA, IgM

B lymphocytes do not differentiate

A

X-linked agammaglobulinemia