Chapter 21

Question 1

glycogen branching occurs every ? residues.

Answer 1

10

Question 2

branching in glycogen

Answer 2

a-1,2. occasional a-1,6

Question 3

catalyzes conversion of G1P to G6P

Answer 3

phosphoglucomutase

Question 4

removes G1P from nonreducing end of glycogen

Answer 4

glycogen phosphorylase

Question 5

debranching enzyme

Answer 5

a-1,6 glucosidase

Question 6

muscle phosphorylase conformation states

Answer 6

active (phosphorylase a or R) and inactive (b or T)

Question 7

glycogen degradation signalling by epinephrine (muscle) or glucagon (liver)

Answer 7

active 7TM receptor > active G protein > cAMP forms from ATP > Active PKA >active phosphoryl kinase > phosphorylase a formed from phosphorylase b. pathway turned off by PP1

Question 8

UDP-glucose formed from

Answer 8

UTP and G1P

Question 9

UDP-glucose formation driven forward by ?

Answer 9

degradation of PPi

Question 10

glycogen synthase reaction

Answer 10

UDP-glucose + glycogen > UDP + glycogen (n+1)

Question 11

initiatior of glycogen synthesis

Answer 11

glycogenin

Question 12

branching is important for ?

Answer 12

increasing solubility

Question 13

affect of activation of protein kinase A

Answer 13

activation of phosphoryl kinase and inactivation of glycogen synthase

Question 14

insulin stimulates glycogenesis by ?

Answer 14

inactivating glycogen synthase kinase which prevents activation of glycogen synthase

Question 15

PP1 function

Answer 15

activates glycogen synthase