chapter 20 - blood cells + circulation Flashcards

1
Q

Blood vessel wall layers

A

Tunica intima - innermost; endothelial lining and underlying connective tissue with elastic membrane (AKA internal elastic membrane in arteries)
Tunica media - middle; concentric sheets of smooth muscle in loose connective tissue with external elastic membrane (arteries only); contains smooth muscle responsible for dilation/constriction
Tunica externa - outermost; connective tissue sheath; anchors vessel to adjacent tissues; contains collagen and elastic fibers +smooth muscle (in veins)

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2
Q

veins (functions + morphology)

A

Veins - return blood to heart
HIGH compliance and LOW elastance compared to arteries
Larger in diameter than arteries, have thinner walls with less elastin and much lower blood pressure

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3
Q

arteries (function + morphology)

A

Arteries - carry blood away from heart
Elasticity - allows arteries to absorb+store pressure waves from heartbeat
Contractility - change vessel diameter via sympathetic division of ANS
Vasoconstriction - contraction of arterial smooth muscle; shrink lumen
Vasodilatation - relaxation of arterial smooth muscle; enlarging the lumen

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4
Q

elastic arteries/conducting arteries

A

1-2.5 cm
Large vessels (pulmonary trunk and aorta)
Tunica media has MANY elastic fibers and few muscle cells; even out pulse

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5
Q

muscular arteries/distribution arteries

A
0.3-1 cm
Medium sized (most arteries); tunica media has many muscle cells
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6
Q

arterioles

A

no longer a pulse, rather even flow

10 microm-0.3mm

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7
Q

venules

A

(internal diameter 8-100 microm)
Very small veins
Carry blood from capillaries
Small ones (<50 microm) LACK tunica media

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8
Q

medium-sized veins

A

(2-9 mm)
Thin tunica media and few smooth muscle cells
Tunica externa with longitudinal bundles of elastic fibers

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9
Q

large veins

A

> 9 mm
thick tunica externa
thin tunica media

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10
Q

GENERAL structure/function of capillaries

A

function: location of all exchange functions fo cardiovascular system
strucutre: endothelial tube inside thin basal lamina. ONLY TUNICA INTIMA. 8-10 micrometer diameter

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11
Q

CONTINUOUS capillaries structure/function

A

structure: complete endothelial lining
most common and LEAST permeable
tight junctions and desmosomes join epithelial cells
gaps of unjoined membranes (intercellular clefts) allow small molecules in/out of capillaries
function: permit diffusion of water, small solutes, and lipid-soluble materials while blocking plasma, proteins, and blood cellls

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12
Q

FENESTRATED capillaries

A

structure: have pores in endothelial lining
function: permit rapid exchange of water and larger solutes between plasma and interstitial fluid w/in choroid plexuses, endocrine organs, kidneys, and intestinal tract

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13
Q

SINUSOID capillaries

A

structure: gaps BETWEEN adjacent endothelial cells
function: permit free exchange of water, LARGE plasma proteins, and blood cells w/in liver, spleen, bone marrow, and endocrine organs

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14
Q

where is most blood found at rest; how does its distribution change during hemorrhaging or vigorous exercise?

A

at rest, most blood is found at blood reservoir : systemic veins contain ~65% of total blood volume
the blood reservoir can constrict during hemorrhage to keep volume in capillaries and arteries near normal

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15
Q

blood pressure in pulmonary circulation, arterial side of systemic circulatory system, at the arteriole side of capillary, venule of capillary, and in veins

A
PC: ~15/8 mmHg
arterial side: ~120-80 mmHg
arteriole side: 53 mmHg
venule: 15-18 mmHg
veins: ~15-18 mmHg
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16
Q

what aids venous return to the heart in the systemic circulatory system?

A

skeletal muscle pump + abdominothoracic/respiratory pump

17
Q

how does change in vessel diameter affect blood flow?

A

flow is proportional to r4, thus small changes in vessel diameter lead to large changes in flow

18
Q

change in blood from aging

A

decreased hematocrit
peripheral blockage by blood clot (thrombus)
pooling of blood in legs (due to venous valve deterioration)

19
Q

changes in heart due to aging

A

reduces max. cardiac output
changes in nodal and conducting cells
reduces elasticity of cardiad(fibrous) skeleton
progressive atherosclerosis
replacement of damaged cardiac muscle cells by scar tissue

20
Q

changes in blood vessels due to aging

A

arteries become less elastic, leading to aneurysms
calcium deposits on vessel walls can lead to stroke or infarct
thrombi can form at athersclerotic plaques