Chapter 20 Flashcards
The human female determines the sex of her offspring.
TRUE or FALSE
The human female determines the sex of her offspring.
Answer:FALSE
How many autosomal chromosomes are present in human cells? A. 23 pair B. 46 C. 22 pair D. 2 pair
How many autosomal chromosomes are present in human cells?
C. 22 pair
What type of genetic change occurs when an allele is silenced by methylation of cytosine bases? A. genomic B. epigenetic C. mutation D. None of the choices is correct.
What type of genetic change occurs when an allele is silenced by methylation of cytosine bases?
B. epigenetic
What type of genes are found on the Y chromosome? A. X-transposed genes B. degenerate genes C. testis-specific genes D. All of the choices are correct.
What type of genes are found on the Y chromosome?
D. All of the choices are correct.
Genomic imprinting allows for differing expressions of an allele.
TRUE or FALSE
Genomic imprinting allows for differing expressions of an allele.
TRUE
Epigenetic changes can not be passed on to a zygote.
TRUE or FALSE
Epigenetic changes can not be passed on to a zygote.
FALSE
Regions of DNA that read the same forward as backward are called \_\_\_\_\_\_ and include the testisspecific genes on the Y chromosome. A. palindromes B. autosomes C. haploid D. genomic
Regions of DNA that read the same forward as backward are called ______ and include the testisspecific
genes on the Y chromosome.
A. palindromes
Barr bodies are normally only found in the cells of female mammals.
TRUE or FALSE
Barr bodies are normally only found in the cells of female mammals.
TRUE
A fertilized egg is called a/an A. autosome. B. zygote. C. ovum. D. Barr body.
A fertilized egg is called a/an
B. zygote.
Which of the following would be found in normal somatic cells of women but not men? A. an X chromosome B. a Y chromosome C. a Barr body D. 22 pairs of autosomal chromosomes
Which of the following would be found in normal somatic cells of women but not men?
C. a Barr body
Cryptorchid males do not produce testosterone.
TRUE or FALSE
Cryptorchid males do not produce testosterone.
FALSE
Deletion of the SRY gene would cause male fetuses to develop as females.
TRUE or FALSE
Deletion of the SRY gene would cause male fetuses to develop as females.
TRUE
Patients with Turner’s syndrome have 47 chromosomes and appear female.
TRUE or FALSE
Patients with Turner’s syndrome have 47 chromosomes and appear female.
FALSE
Leydig cells in the male produce Müllerian inhibition factor.
TRUE or FALSE
Leydig cells in the male produce Müllerian inhibition factor.
FALSE
What is the principle sex steroid in males? A. estrogen B. testosterone C. progesterone D. aldosterone
What is the principle sex steroid in males?
B. testosterone
How many chromosomes are found in a normal human cell? A. 23 B. 23 pair C. 46 D. Both 23 pair and 46 are correct.
How many chromosomes are found in a normal human cell?
D. Both 23 pair and 46 are correct.
Female accessory sex organs develop from the mesonephric ducts.
TRUE or FALSE
Female accessory sex organs develop from the mesonephric ducts.
FALSE
Treating a male fetus with antibodies to DHT would prevent development of the epididymides.
TRUE or FALSE
Treating a male fetus with antibodies to DHT would prevent development of the epididymides.
FALSE
Dihydrotestosterone is produced by the action of the enzyme 5 alpha-reductase on testosterone.
TRUE or FALSE
Dihydrotestosterone is produced by the action of the enzyme 5 alpha-reductase on testosterone.
TRUE
Female accessory organs develop because of the presence of ovaries.
TRUE or FALSE
Female accessory organs develop because of the presence of ovaries.
FALSE
A lack of testosterone in males will cause the genital tubercle to form a(n) A. penis. B. testis. C. clitoris. D. ovary.
A lack of testosterone in males will cause the genital tubercle to form a(n)
C. clitoris.
The first event to occur during development of the reproductive system would be the
A. descent of the testes into the scrotum.
B. formation of the vagina.
C. onset of testosterone production.
D. development of the Müllerian ducts.
The first event to occur during development of the reproductive system would be the
D. development of the Müllerian ducts.
Testosterone, not DHT, stimulates embryonic development of A. seminal vesicles. B. ductus deferens. C. ejaculatory duct. D. All of the choices are correct.
Testosterone, not DHT, stimulates embryonic development of
D. All of the choices are correct.
Males lacking testosterone receptors would
A. develop as genotypic females.
B. have testes and female external genitalia.
C. lack gonads.
D. have male internal genitalia.
Males lacking testosterone receptors would
B. have testes and female external genitalia.
The embryonic urethral fold becomes the female A. labia minora. B. labia majora. C. glans clitoris. D. All of these choices are correct.
The embryonic urethral fold becomes the female
A. labia minora.
The most common cause of female pseudohermaphroditism is congenital adrenal hyperplasia.
TRUE or FALSE
The most common cause of female pseudohermaphroditism is congenital adrenal hyperplasia.
TRUE
Those with testicular feminization syndrome have A. an extra X chromosome. B. a missing X chromosome. C. an extra chromosome 23. D. no chromosomal number abnormalities.
Those with testicular feminization syndrome have
D. no chromosomal number abnormalities.
Testosterone levels in the male embryo and fetus are very high throughout the prenatal period.
TRUE or FALSE
Testosterone levels in the male embryo and fetus are very high throughout the prenatal period.
FALSE
A male with 5 alpha-reductase deficiency will have male internal sex organs but more female
appearing external genitals.
TRUE or FALSE
A male with 5 alpha-reductase deficiency will have male internal sex organs but more female
appearing external genitals.
TRUE
During the first trimester of pregnancy, the ovaries are active endocrine glands.
TRUE or FALSE
During the first trimester of pregnancy, the ovaries are active endocrine glands.
FALSE
Gonadotropic hormones from the anterior pituitary will affect the gonads in all of the following ways
EXCEPT
A. stimulation of spermatogenesis or oogenesis.
B. stimulation of gonadal hormone secretion.
C. development of internal genital ducts.
D. maintenance of gonad structures.
Gonadotropic hormones from the anterior pituitary will affect the gonads in all of the following ways
EXCEPT
C. development of internal genital ducts.
The rate at which GnRH is secreted from the hypothalamus determines whether LH or FSH is secreted
from the anterior pituitary.
TRUE or FALSE
The rate at which GnRH is secreted from the hypothalamus determines whether LH or FSH is secreted
from the anterior pituitary.
TRUE
Inhibin prevents release of LH from the anterior pituitary.
TRUE or FALSE
Inhibin prevents release of LH from the anterior pituitary.
FALSE
The gonads have a negative feedback effect on gonadotropins of the anterior pituitary.
TRUE or FALSE
The gonads have a negative feedback effect on gonadotropins of the anterior pituitary.
TRUE
Synthetic analogues of GnRH are useful in treating benign prostatic hyperplasia and
endometriosis.
TRUE or FALSE
Synthetic analogues of GnRH are useful in treating benign prostatic hyperplasia and
endometriosis.
TRUE
The secretion of GnRH, FSH, and LH are pulsatile instead of continuous.
TRUE or FALSE
The secretion of GnRH, FSH, and LH are pulsatile instead of continuous.
TRUE
In general, the onset of puberty occurs sooner in boys compared to girls.
TRUE or FALSE
In general, the onset of puberty occurs sooner in boys compared to girls.
FALSE
The first sign of puberty in females is A. breast development. B. menarche. C. growth spurt. D. axillary hair.
The first sign of puberty in females is
C. growth spurt.
What event(s) occur to start puberty?
A. GABA release in hypothalamus is reduced.
B. Glutamate stimulation of the hypothalamus is increased.
C. Increased secretion of GnRH to the anterior pituitary.
D. All of the choices are correct.
What event(s) occur to start puberty?
D. All of the choices are correct.
Epiphyseal growth in males is stimulated by estrogen.
TRUE or FALSE
Epiphyseal growth in males is stimulated by estrogen.
TRUE
Pubic and axillary hair growth at puberty is from increased secretion of
A. anterior pituitary gonadotropins.
B. estrogen and testosterone from the onads.
C. androgens from the adrenal cortex.
D. melatonin from the pineal gland.
Pubic and axillary hair growth at puberty is from increased secretion of
A. anterior pituitary gonadotropins.
The role of melatonin in puberty of humans is well established and critical.
TRUE or FALSE
The role of melatonin in puberty of humans is well established and critical.
FALSE
Longitudinal growth during development is dependent on estrogen stimulation of the epiphyseal
growth plates in both males and females.
TRUE or FALSE
Longitudinal growth during development is dependent on estrogen stimulation of the epiphyseal
growth plates in both males and females.
TRUE
Women who are very lean and physically active may have irregular cycles and amenorrhea.
TRUE or FALSE
Women who are very lean and physically active may have irregular cycles and amenorrhea.
TRUE
In males androgens are required for
A. initiation of spermatogenesis at puberty.
B. regression of the wolffian ducts during embryonic development.
C. maintenance of accessory sex organs.
D. development of the Müllerian ducts.
In males androgens are required for
C. maintenance of accessory sex organs.
Which of the following is a precursor to melatonin synthesis?
A. tryptophan
B. serotonin
C. tyrosine
D. Both tryptophan and serotonin are correct.
Which of the following is a precursor to melatonin synthesis?
A. tryptophan
The correct order of the four phases of sexual response in both sexes would be
A. excitation, plateau, orgasm, resolution.
B. plateau, excitation, orgasm, resolution.
C. orgasm, excitation, resolution, plateau.
D. resolution, plateau, excitation, orgasm.
The correct order of the four phases of sexual response in both sexes would be
A. excitation, plateau, orgasm, resolution.
Women do not enter a refractory period following orgasm and are capable of multiple orgasms.
TRUE or FALSE
Women do not enter a refractory period following orgasm and are capable of multiple orgasms.
TRUE
Match the event to the phase of sexual response.
- resolution
- excitation
- orgasm
- plateau
A.Erection of penis and clitoris
ejaculation in males and B.Contraction of vagina in females
C.Return to pre-excitement condition
D.Plateau engorgement of labia with blood
Match the event to the phase of sexual response.
- resolution
- excitation
- orgasm
- plateau
A.Erection of penis and clitoris-2
ejaculation in males and B.Contraction of vagina in females-3
C.Return to pre-excitement condition-1
D.Plateau engorgement of labia with blood-4
The majority of the testis is comprised of A. Leydig cells. B. interstitial cells. C. Sertoli cells. D. seminiferous tubules.
The majority of the testis is comprised of
D. seminiferous tubules.
Sertoli cells are stimulated by \_\_\_\_\_\_\_\_\_\_, while Leydig cells are stimulated by \_\_\_\_\_\_\_\_. A. FSH, LH B. LH, FSH C. testosterone, LH D. FSH, testosterone
Sertoli cells are stimulated by __________, while Leydig cells are stimulated by ________.
A. FSH, LH
In males, conversion of testosterone to estrogen in the brain is essential for normal regulation of LH
secretion.
TRUE or FALSE
In males, conversion of testosterone to estrogen in the brain is essential for normal regulation of LH
secretion.
TRUE
What enzyme is needed for the conversion of testosterone into estradiol in the male brain? A. 5-alpha reductase B. aromatase C. ATPase D. cGMP phosphodiesterase
What enzyme is needed for the conversion of testosterone into estradiol in the male brain?
B. aromatase
Secretion of LH is inhibited by
A. high concentrations of inhibin.
B. rapidly rising concentrations of estradiol.
C. high concentrations of testosterone.
D. decreasing concentrations of progesterone.
Secretion of LH is inhibited by
C. high concentrations of testosterone.
In males, the levels of testosterone decline drastically with age.
TRUE or FALSE
In males, the levels of testosterone decline drastically with age.
FALSE
Developing sperm cells produce estrogen that may serve to regulate their environment.
TRUE or FALSE
Developing sperm cells produce estrogen that may serve to regulate their environment.
TRUE
Male androgens A. stimulate protein synthesis and muscle growth. B. stimulate bone growth. C. stimulate erythropoiesis. D. All of the choices are correct.
Male androgens
D. All of the choices are correct.
Estrogen may play a role in spermatogenesis as evidenced by estrogen receptors found on developing A. sperm cells. B. brains. C. uterine. D. oocytes.
Estrogen may play a role in spermatogenesis as evidenced by estrogen receptors found on
developing.
A. sperm cells.
Damage to the Sertoli cells would result in the production of antibodies against sperm cells.
TRUE or FALSE
Damage to the Sertoli cells would result in the production of antibodies against sperm cells.
TRUE
The Leydig cells of the testes constitute a blood-testis barrier that prevents autoimmune destruction of
the sperm.
TRUE or FALSE
The Leydig cells of the testes constitute a blood-testis barrier that prevents autoimmune destruction of the sperm.
FALSE
Secretions of the Sertoli cells and cells of Leydig influence the functions of each other.
TRUE or FALSE
Secretions of the Sertoli cells and cells of Leydig influence the functions of each other.
TRUE
What occurs during spermiogenesis? A. chromosomes are compacted by protamines B. flagellum and acrosome form C. cytoplasm removed by Sertoli cells D. All of the choices are correct.
What occurs during spermiogenesis?
D. All of the choices are correct.
After meiosis I in males, \_\_\_\_\_\_\_\_ are formed. A. primary spermatocytes B. secondary spermatocytes C. spermatids D. spermatozoa
After meiosis I in males, ________ are formed.
B. secondary spermatocytes
Apoptosis of T lymphocytes requires that Sertoli cells produce A. FAS ligand. B. androgen-binding protein. C. testosterone. D. All of these choices are correct.
Apoptosis of T lymphocytes requires that Sertoli cells produce
A. FAS ligand.
Spermatogenesis is regulated by A. FSH. B. testosterone and its derivatives. C. growth hormone. D. progesterone.
Spermatogenesis is regulated by
B. testosterone and its derivatives.
Which of the following is NOT a function of Sertoli cells?
A. production of androgen-binding protein
B. FSH stimulation of spermiogenesis
C. protection of developing sperm from the male’s immune system
D. production of testosterone
Which of the following is NOT a function of Sertoli cells?
D. production of testosterone
FSH is necessary for spermiogenesis to occur.
TRUE or FALSE
FSH is necessary for spermiogenesis to occur.
FALSE
Tight junctions between \_\_\_\_\_\_\_\_\_\_\_ are responsible for the formation of the blood-testis barrier. A. Leydig cells B. Sertoli cells C. spermatogonial cells D. trophoblast cells
Tight junctions between ___________ are responsible for the formation of the blood-testis barrier.
B. Sertoli cells