Chapter 2 : Policies , Guidelines, and Regulations in animal research

Question 1

What must accompany a dog , cat or nonhuman primate that is transported by a research facility ?

Answer 1

Health certificate stating the animals have recently been examined by a veterinarian and are healthy.

Question 2

What document must an institution which houses USDA covered animals submit to the USDA each year ?

Answer 2

An annual report to the USDA

Question 3

Who may conduct an unannounced inspection of registered institution ?

Answer 3

The VMO “Veterinary Medical Officers”

Question 4

The institutional official is the person designated by an institution to do which of the following ?

Answer 4

Take responsibility for making sure the organization complies with the AWA

Question 5

Which feature is required to be provided for dogs by the animal welfare act (AWA) ?

Answer 5

An exercise program

Question 6

List 3 methods of identifying adult animals at a research institution ?

Answer 6

Tag and collar
Microchip
Ear Tag

Question 7

If an animal was used in teaching, research, experiments, or tests that caused no pain or distress and did not require the use of pain relieving drugs, under what USDA pain category would it be classified as?

Answer 7

Category C

Question 8

According to the USDA satellite facilities are areas of containment outside of a core facility or other centrally designated or managed area in which animals are housed for more than _______ hours ?

Answer 8

12

Question 9

Who can restrict or withdraw approval of the animal welfare assurance if an institution does not fulfill its responsibilities ?

Answer 9

Office of Laboratory Animal Welfare

Question 10

What documentation must accompany all dogs, cats, or NonHuman primates that are shipped to a research institution?

Answer 10

A health certificate stating the animals have been inspected by a veterinarian and found to be healthy

Question 11

What procedures may be recorded on herd health records for agriculture laboratory animals ?

Answer 11

Routine husbandry and preventative medical procedures such as vaccinations

Question 12

What would NOT be recorded on an Animals health record ?

Answer 12

An animal exercise program

Question 13

OLAW

Answer 13

Publishes the policy on the humane care and use of laboratory animals

Question 14

AAALAC International

Answer 14

Provides peer evaluation of animal care and use program

Question 15

AWR

Answer 15

Describes what a facility must do to comply with the AWA

Question 16

FDA

Answer 16

Requires compliance with the GLPs

Question 17

USDA

Answer 17

Registers institutions using species covered by the AWA

Question 18

What agency enforces the PHS policy ?

Answer 18

OLAW

Question 19

What document is signed by the Institutional official and is filed with OLAW to commit the institution to compliance with the PHS policy ?

Answer 19

Animal welfare assurance

Question 20

What animals are covered under the PHS Policy ?

Answer 20

All vertebrates

Question 21

Which of the following is NOT required by the PHS policy ?

Answer 21

Annual inspection of animal facilities

Question 22

Which organization is responsible for monitoring compliance with PHS policy ?

Answer 22

Office of Laboratory animal welfare (OLAW)

Question 23

What is the agreement made by a research institution that outlines how it complies with the PHS policy ?

Answer 23

Animal welfare assurance

Question 24

Which statement is FALSE about federal protection of animals used for research, testing, or teaching ?

Answer 24

The AWA and AWR covers cattle used in agricultural studies.

Question 25

Which animals are covered under the animal welfare act and Regulations ?

Answer 25

WIld mice

Question 26

How frequently does the Guide specify that the IACUC review the entire animals care and use program including an inspection ?

Answer 26

At least Once a year

Question 27

What document can be used to meet the requirement for an OLAW semiannual program evaluation and report ?

Answer 27

An AAALAC site visit report

Question 28

Which state has passed legislation, starting in 2020, that prohibits the sale of cosmetic products and ingredients that have been tested on animals ?

Answer 28

California

Question 29

The word _____________is used in the Guide to describe aspects of a program that are essential or imperative to humane care and use of laboratory animals ?

Answer 29

Must

Question 30

The word ___________ is used in the guide to describe aspects of a program that are strong recommendations to achieve a goal.

Answer 30

should

Question 31

The Guide uses the word _________ to indicates a suggestion to be considered.

Answer 31

May

Question 32

Which organization uses the Guide as one of its standards for the accreditation of laboratory animal programs ?

Answer 32

AAALAC international

Question 33

In an animal research facility, the primary program management and oversight responsibility falls to the ________ who provides leadership to program personnel, The _________who is responsible for the health and wellbeing of the animals in the program and the ________that reviews and approves proposed animal use protocols and amendments.

Answer 33

Institutional official Attending Veterinarian IACUC

Question 34

If animals are to be euthanized at the end of a study the method of euthanasia must be in accordance with the guidelines set up by which organization of agency ?

Answer 34

American Veterinarian Medical Association

Question 35

Which animals are NOT required by law to be accompanied by a health certificate when being shipped domestically ?

Answer 35

Laboratory Mice

Question 36

According to the AVMA guidelines for the Euthanasia of animals, what step must be taken before the disposal of an animals carcass ?

Answer 36

Death Must be confirmed

Question 37

The USDA requires that NonHuman primates be shipped with a health certificate . if FALSE explain why

Answer 37

True

Question 38

Which document is used by AAALAC international and USDA when inspecting agricultural animals used in biomedical research.

Answer 38

Guide for care and use of agricultural animals in research and teaching

Question 39

What specific state regulations must met regarding the sale and shipment of dogs ?

Answer 39

Rabies vaccination requirements

Question 40

How many Biosafety levels are described in the BMBL ?

Answer 40

4. (BSL 1-4)

Question 41

A_________ includes the animals or other entity that is administered a substance

Answer 41

Test system

Question 42

The ___________ is the person responsible for all aspects of a study

Answer 42

Study director

Question 43

The _________ audits studies to ensure compliance with GLPs

Answer 43

quality assurance unit

Question 44

The________is a detailed description of a procedure to be performed. These help to ensure standardization of procedures.

Answer 44

Standard operating procedure

Question 45

The observations, measurements and specimens related to a study are called the ________________.

Answer 45

Raw Data

Question 46

The two federal agencies that require compliance with the GLPs are the ____________ and the ______________.

Answer 46

EPA ( environmental protection agency) FDA ( food and drug administration)

Question 47

What is a quality assurance units responsible for ensuring compliance with ?

Answer 47

Good Laboratory Practice (GLP)

Question 48

Which statement is FALSE about studies conducted in a compliance with GLP Regulations.

Answer 48

Animals on different GLP studies must be housed in separate rooms

Question 49

GLP data archives are kept for __________ years after study completion if they support a research or marketing permit that was not approved but they are kept for __________years after study completion if the study is not submitted for a marketing permit or is discontinued .

Answer 49

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