CHAPTER 1: ANIMAL RESEARCH, FUNDING & PROGRAM OVERSIGHT Flashcards
Carl Linnaeus developed a system to classify organisms based on their anatomical traits called ?
taxonomy
The first step in scientific research is to establish a hypothesis. If FALSE explain why ?
The 1st step is to define the question to be investigated.
In the US, who grants approval to market a new drug after several rounds of clinical trials ?
Food and Drug Administration (FDA)
What type of information is usually included in a grant application ?
Detailed description of the research goals,
scientific basis of the study,
any preliminary data and results,
all procedures to be performed.
How many years does a typical grant provide money for funding of a research project?
3-5 years
What information is NOT typically provided in a grant application ?
A search for alternatives to potentially painful procedures
The purpose of a grant application is to request _______________. ?
Money to Conduct Research
Animals may be used for research after an animal use protocol is submitted to the IACUC. if FALSE explain why.
No work involving animals can be started until the animals use protocol have been approved by the IACUC.
IACUC’s are required by which of the following?
Federal Law
What is not a Duty of the IACUC ?
Training research staff
List 6 types of information included in a typical animal use protocol ?
-Rationale and purpose for using animals.
-Justification for species and number of animals used.
-List of personnel assigned to conduct procedures under the protocol , including training and qualifications.
-Complete description of procedures to be performed
-Confirm the study isn’t a duplication of other experiments.
-Intended methods of Euthanasia.
Per the animal welfare regulations, how long is a protocol using USDA covered species approved for ?
One year
Which entity reviews animal use protocol to ensure compliance with all relevant laws and regulations and institutional policies on animal welfare?
Institutional Animal Care and use Committee ( IACUC)
What does the IACUC have the authority to do ?
Stop a previously approved animal use protocol
How often does the animal welfare regulations require the IACUC to monitor the animal care and use program through reviews of the program and routine inspections of the animal facilities ?
At least every 6 Months
What 3 entities require that the IACUC ensures the institution and its personnel comply with all relevant mandates for animal welfare thus enforcing self regulation ?
USDA
OLAW
AALAC International
The IACUC must have the APPROVAL of the institutional official to suspend a study involving the use of animals. If FALSE explain why ?
False, The IACUC has the authority to suspend any animal related activity, including an entire protocol.
List 3 activities that are performed during post approval monitoring ?
-Observe procedures
-Review animal Health records
-Inspect animal use areas
What information does an institution provide to AAALAC international to describe its animal research program and facilities ?
Animal care and use policies and responsibilities ,IACUC activities and administrations, animal environment, housing and management. veterinary medical care, physical plant information.
