Chapter 2 - Immunity and the Non-specific Immune System Flashcards
1
Q
- Best examples of natural passive VS natural active immunity
A
PLACENTAL TRANSFER AND RECOVERY
2
Q
- Best examples of artificial passive VS artificial active immunity
A
ANTIBODY/ANTITOXIN ADMINISTRATION and VACCINATION (ANTIGENIC STIMULATION)
3
Q
- Ingestion of particulate matter such as bacteria by a cell
A
PHAGOCYTOSIS
4
Q
- Internalization of fluids and solutes by a cell
A
PINOCYTOSIS
5
Q
- Name the tissue macrophages of the ff: liver, connective tissue, kidney, brain, joints, lungs, epidermis
A
KUPFFER, HISTIOCYTES, MESANGIAL, MICROGLIAL, SYNOVIAL ‘A’, ALVEOLAR, LANGERHANS
6
Q
- Cell surface receptors important for the attachment of pathogens in phagocytosis
A
- FORMYL-METHIONYL-LEUCYL-PHENYLALANINE (FMLP) RECEPTOR
- CR3 RECEPTOR, - - LAMININ RECEPTOR
7
Q
- Other term of “digestion” by phagocytes
A
CYTOPEPSIS
8
Q
- Cell surface proteins that promote cell-to-cell interaction to enhance phagocytosis
A
INTEGRINS
9
Q
- Substances that coat particles and other organisms making them more susceptible to phagocytosis
A
OPSONINS
10
Q
- An opsonin that acts like a glue to cause neutrophils and their targets to stick together
A
FIBRONECTIN
11
Q
- An opsonin that enhances the interaction of phagocytes and antibody-coated particle
A
CRYSTALLIZABLE FRAGMENT (Fc) OF IMMUNOGLOBULIN
12
Q
- The 5 cardinals of inflammation
A
RUBOR TUMOR COLOR DOLOR FUNCTIO LAESA
13
Q
- Stages of inflammation
A
VASCULAR RESPONSE, CELLULAR RESPONSE, CELLULAR PROLIFERATION AND REPAIR
14
Q
- Complement split product that functions as chemoattractant for phagocytes
A
C5a
15
Q
- Identify the type I and II interferons and their origin
A
Type I:
> IFN-alpha (MACROPHAGES and OTHER LEUKOCYTES)
> IFN-beta (FIBROBLASTS);
Type II:
> IFN-gamma/immune IFN (T-CELLS)
16
Q
- An AA released by ruptured platelets which are directed as cationic detergent against gram-pos bacteria
A
BETA LYSINE
17
Q
- Two iron storage proteins that competes bacteria for iron
A
LACTOFERRIN & TRANSFERRIN
18
Q
- Enzyme found in milk and saliva that catalyzes the conversion of hydrogen peroxide to water and oxygen
A
LACTOPEROXIDASE
19
Q
- Enzyme that hydrolyzes the mucopeptide layer of the bacterial cell wall leading to osmotic lysis
A
LYSOZYME
20
Q
- Composition of NK cells in the peripheral blood
A
10-15%
21
Q
- NK cells are absent in what lymphoid organ
A
LYMPH NODES
22
Q
- Pore-forming protein released by CTLs and NK cells
A
PERFORIN
23
Q
- Subset of killer cells that can lyse target cells coated with antibodies w/o the participation of complement
A
ANTIBODY-DEPENDENT CYTOTOXIC CELLS (ADCC)
24
Q
- CD marker for ADCC
A
CD16
25
Q
- Lymphocyte induced into cytotoxic state by IL-2
A
LYMPHOKINE-ACTIVATED KILLER CELL (LAK)
26
Q
- Tumor-specific t-cells and have tumoricidal activity
A
TUMOR INFLITRATING LYMPHOCYTE (TIL)
