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Immunology & Serology (P.R.) > Chapter 1 - History > Flashcards

Chapter 1 - History Flashcards

1
Q
  1. Greek philosopher: “individuals who recovered from plague RARELY contracted the disease again”
A

Thucydides

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2
Q
  1. Inhalation of powdered crust from smallpox lesions
A

Chinese

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3
Q
  1. “variolation”
A

Lady Montagu

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4
Q
  1. “vaccination”
A

Edward Jenner

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5
Q
  1. “pasteurization” ; resistance to fresh culture Pasteurella multocida from injection of old cuture
A

Louis Pasteur

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6
Q
  1. Cellular (phagocytic) theory of immunity
A

Elie Metchnikoff

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7
Q
  1. First proof of humoral immunity theory
A

Emil von Behring & Shibasaburo Kitasato

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8
Q
  1. “passive immunization”
A

Emil Roux

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9
Q
  1. Resolved the conflict between cellular and humoral theories
A

Sir Almroth Wright & S.R. Douglas

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10
Q

Publisher and doctrine of humoral immunity theory

A

Paul Ehrlich

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11
Q

Complement fixation

A

Bordet and Gengou

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12
Q

Passive hemagglutination

A

Boyden

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13
Q

Plaque formation by immunocompetent cells in agar gel

A

Jerne, Henry, and Nordin

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14
Q

Rosette formation

A

Biozzi and Zaalberg

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15
Q

Fluorescent-labelled Ag and Ab

A

Coons

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16
Q

Radioactive-labelled Ag and Ab

A

Yalow and Berson

17
Q

Enzyme-labelled Ag and Ab

A

Avrameas and Uriel

18
Q

Ring disk test

19
Q

Used ring disk test in antrhax diagnosis

20
Q

Simple diffusion method (quantitation for Ag-Ab complex)

21
Q
  1. Double diffusion method (quali)
A

Ouchterlony and Elek

22
Q
  1. Immunoelectrophoresis analysis in gels
A

GRABAR and WILLIAMS

23
Q
  1. Quantitative modification of immunoelectrophor
A

RESSLER and LAUREL

24
Q
  1. “prophylaxis phenomenon” discovery
A

CHARLES RICHET and PAUL PORTER

25
Q
  1. “serum sickness”
A

CLEMENS VON PIRQUET and BELA SCHICK

26
Q
  1. Local or systemic vasculitis caused by an initial exposure to endotoxin producing intravascular fibrin thrombi whose clearance results in reticuloendothelial blockade leading to tissue necrosis or hemorrhage
A

SCHWARTZMAN RXN/PHENOMENON

27
Q
  1. Reaginic Abs adhering to tissue cells that can mediate histamine and serotonin release on contact with the allergen
A

PRAUSNITZ-KUSTNER RXN (Paul and Heinz)

28
Q
  1. “histamine is present in mast cells”
A

RILEY and WEST

29
Q
  1. Side chain theory
30
Q
  1. Template theory of antibody formation
A

FRIEDRICH BREINL and FELIX HAUROWITZ

31
Q
  1. Clonal selection theory; human immunodeficiency discovery
A

NIELS K. JERNE and FRANK MACFARLANE

32
Q
  1. HLA on leukocytes
A

J. DAUSSET and F. RAPAPORT

33
Q
  1. Cooperation of B and T cells
A

H.N. CLAMAN

34
Q
  1. Produced hybridoma
A

C. MILSTEIN and G.J.F. KOHLER

Immunology & Serology (P.R.) (5 decks)

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