Chapter 2 and 3 Flashcards
Which generation is allowed to self-fertilize
F1
F2 generation possessed what ration
9:3:3:1
how to do multiplication method
Multiply 3 outcomes together
Multiplication method
Outcomes
Fork line
Probablities
How to do fork line method
Multiply probabilities of each phenotype
Pedigree purpose
Inheritance patters in humans
Probability equation
Number of times an outcome occurs/ total number of possible outcomes
The accuracy of probability calculation is determined by
sample size
Product rule
Probability that two or more independent events will occur = product of individual properties
Binomial expansion equation
Probability of an unordered combination of outcomes
What is binary fission
Forming a wall down center of cell
What is result of binary fission
Two daughter cells that are genetically identical
Majority of eukaryotic cells are
Diploid
Homologous chromosomes have a similar sequence and genes, but different _____
Alleles of the genes
Which chromosomes are not homologous
sex chromosomes
Genes on homologous chromosomes also have the same
Locus
What phases are interphase
G1, S, G2, M
Interphase
Duplicated chromosome
Prophase
Chromatids formed
Prometaphase
Nuclear membrane fragmented and chromatids attach to mitotic spindle
Telophase
Cleavage furrow formed
Isagamous organisms
Fungi, algae
Produces gametes that are similar
Heterogamous organisms
Produce gametes that are different
Spermatogenesis produces
4 haploid sperm cells
Oogenesis produces
1 single haploid egg cells
what does oogenia do
Begins meiosis, arrests at prophase I
How does division of oocyte happen
splits asymmetrically
Larger cell is secondary oocyte, released during ovulation
If it’s fertilized, it does meiosis II
Chromosome theory of inheritance
Chromosomes contain genetic material
Chromosomes are replicated and passed down from generation to generation
Nuclei of most eukaryotic cells are diploid
During formation of haploid cells, chromosomes segregaed independently
One set of chromosomes is inherited from father, other set from mother
Maternal effect genes
Genotype of mother determines phenotype of offspring
What surrounds oocytes
Nurse cells - transports gene product into oocyte
If DD or Dd is released in oocyte
Dextral coiling
If dd is released in oocyte
sinistral coiling
epigenetic inheritance
modification to nuclear gene that alters expression
Gene expression is not permanently changed over generations
It IS permanently changed in the individual for their life
Epigenetic modifications do NOT change
DNA sequence
Barr body
highly condensed inactive x chromosome structure in the interphase nuclei of somatic cells in female cats that was not found in male cats.
when does X chromosome become inactivated
Randomly, early stage of embryonic development
Mammalian cells can count their C chromosome in their somatic cells and allow
one of them to remain active
If a mammal has more than two X chromosomes
All but one will be deactivated
Where does X inactivation happen
X inactivation center
Initiation phase
Embryonic development
One X chromosome remains active, other is inactive
Spreading phase
Begins from Xic and spreads outwards towards both ends until entire chromosome is inactivated
Maintenance phase
Inactivated X chromosome remains as a Barr body
When cell divides, barr body is replicated, both copies remain compacted
Genetic imprimting
A segment of DNA is marked, mark is retained and recognized throughout life
What phenotype follows non-mendelian inheritance
imprinted genes phenotypes
Monoallelic expression
Offspring will express one of two alleles due to marking
Genomic imprinting involves
DNA methylation
How are genes imprinted through DNA methylation
Imprinting control region (ICR) is located near imprinting gene
Gene imprinting disorders
Prader Willi, Angelman syndrome