Chapter 2 Flashcards

1
Q

Why is water the solvent of life?

A

It is capable of dissolving more substances than any other liquid. It has a high melting point, boiling point, and heat of vaporization. a consequence of attractions between adjacent water molecules that give liquid water great internal cohesion.
It also helps cells transport and use substances like oxygen or nutrients

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2
Q

What does isotonic mean?

A

There is no net water movement, so there is no change in the size of the cell

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3
Q

What does hypertonic mean?

A

Water will leave the cell, and the cell will shrink.

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4
Q

What are the properties of hydrogen bonding?

A

Hydrogen bonding occurs between an electronegative atom (hydrogen acceptor, like oxygen or nitrogen) and a hydrogen atom that is covalently bound to another electronegative atom (hydrogen donor), which can be in the same or another molecule.

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4
Q

What does hypotonic mean?

A

water will enter the cell creating outward pressure, and the cell will swell, possibly bursting.

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5
Q

What is a hydrogen acceptor?

A

an electronegative atom of a neighboring molecule or ion that contains a lone pair that participates in the hydrogen bond.

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6
Q

What is a hydrogen donor?

A

usually a strongly electronegative atom such as N, O, or F that is covalently bonded to a hydrogen bond

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7
Q

What does an amphipathic molecule have?

A

Have both hydrophilic and hydrophobic areas.
Hydrophilic “head group” and hydrophobic alkyl group “tail”

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8
Q

What are the steps of Amphipathic Biomolecules and what happens to entropy throughout?

A
  1. Dispersions of lipids in H2O (each lipid molecule forces surrounding H2O molecules to become highly ordered.
  2. Cluster of lipid molecules (Only lipid portions at the edge of the cluster force the ordering of water. Fewer H2O molecules are ordered, and entropy increases).
  3. Micelles (All hydrophobic groups are sequestered from water; ordered shell of H2) molecules is minimized, and entropy is further increased).
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9
Q

What are hydrophobic interactions?

A

The forces that hold the hydrophobic regions of the amphipathic molecules.

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10
Q

What do water cages do?

A

Water cages form a sort of ‘cage’ around a nonpolar/nonsoluble/hydrophobic molecule because they disrupt the H-bonding network. When this occurs, the molecule is not happy, and entropy drops.

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11
Q

What happens to entropy in amphipathic biomolecules?

A

Initially, entropy drops. As you liberate water, entropy increases.

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12
Q

What is the basis for the pH scale?

A

The ion product of water, Kw

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13
Q

What is pH?

A

A measure of how acidic/basic water is, ranging from 0-14.
7= neutral
pH < 7 acidity
pH>7 base

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13
Q

What is the pH of buffered blood?

A

pH is 7.4

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14
Q

What is acidosis?

A

When pH drops (even a little bit), making there be too much acid in the body. Dangerous!

15
Q

What is alkalosis?

A

When pH levels increase (even a little bit), making there be too much base in the body) Dangerous!

16
Q

What is ketoacidosis?

A

Common in diabetics who don’t treat it, when their insulin levels become too low. Worsened by acidosis.

17
Q

What do strong acids and bases do?

A

Completely ionize in aqueous solution

17
Q

What does the Henderson-Hasselbalch equation tell us?

A

It relates pH, pKa, and buffer concentrations. It calculates the amount of acid and conjugate base to be combined for the preparation of a buffer solution having a particular pH.

18
Q

Strong acid examples

A

HCl, HBr, HI, HNO₃, HClO₄, and H₂SO₄

19
Q

How do pH and strong acids correlate?

A

Strong acids have a lower pH level.
Low pH= stronger acid

20
Q

What is the difference between strong and weak acids?

A

Strong acids and bases completely ionize in aqueous solutions. Weak acids and bases do not completely ionize in solution, and are more important in biological systems.

21
Q

What are proton donors and proton acceptors?

A

Proton donors are acids and proton acceptors are bases. Proton donors and its corresponding proton acceptor make up a conjugate acid-base pair.

22
Q

What do titration curves do and what are the steps to draw one?

A

Help determine pKa. Graphical representation of the pH of a solution during a titration
First draw the titration graph, then add the pKa values, draw the general titration curve, and then answer the questions.

23
Q

How do pH and pKa correlate?

A

The lower the pH, the higher the pKa value will be. The higher the pH, the lower the pKa value

24
Q

What are weak acids and what are some?

A

Acids that don’t completely dissociate in solution
HCOOH
CH3COOH
HF

25
Q

What causes deprotonation?

A

The donation of electrons or acceptance of the proton using a base, which forms its conjugate acid.

26
Q

What happens when pKa is low?

A

It is easier to deprotonate an acid