Chapter 19: Gene Expression in Development Flashcards
Development
process by which a multicellular organism, beginning with a single cell, goes through a series of changes, talking on successive forms that characterize it’s life cycle
embryo
earliest stages of development in a plant or animal
Determination
sets the developmental fate of a cell—what type of cell it will become—even before any characteristics of that cell type are observable
Differentiation
is the process by which different types of cells arise, leading to cells with specific structures and functions
Morphogenesis
organization and spatial distribution of differentiated cells into the multicellular body and its organs
Growth
increase in size of the body and its organs by cell division and cell enlargement
Cell fate
During development, each undifferentiated cell will become part of a particular type of tissue
totipotent
cells have the potential to differentiate into any cell type, including more embryonic cells
pluripotent
have the potential to develop into most other cell types, but cannot form new embryos
multipotent
differentiate into several different, related cell types.
unipotent
they can produce only one cell type, they own
cytoplasmic segregation (unequal cytokinesis)
factor within the cell may be unequally distributed in the cytoplasm. After cell division, the factor ends up in some daughter cells or region of cells but not others.
Induction (cell-to-cell communication)
factor is actively produced and secreted by certain cells to induce other cells to become determined
cytoplasm determinants
distributed unequally in eggs cytoplasm. plays role in directing the embryonic development of many organisms
inducer
signaling factor
pattern formation
process that results in the spatial organization of a tissue or organism
organ identity genes
encode proteins that act in combination to produce specific whorl features
homeotic mutation
replacement of one organ for another
positional information
“spatial” sense
morphogen
which diffuses from one cell or group of cells to surrounding cells, setting up a concentration gradient
Maternal effect genes
set up the major axes (anterior–posterior and dorsal–ventral) of the egg
Segmentation genes
determine the boundaries and polarity of each segment.
Hox genes
determine which organ will be made at a given location
Gap genes
organize borad areas along the anterior-posterior axis
Pair rule genes
divide the embryo into units of two segments each
segment polarity genes
etermine the boundaries and anterior–posterior organization of the individual segments.
homeobox
common 180 base pair sequence
homeodomain
60 amino acid sequenced, encoded by the homeobox
blastocyst
in both mice and humans, a slightly embryonic stage is a hollow sphere of cells
embryonic stem cells
can be removed from the blastocyst and grown in lab cultures
induced pluripotent stem cells
altered skin cells pluripotent and could be induced to differentiate into many tissues