CHAPTER 19 Flashcards
its the Central metabolic pathway and plays a key roles in aerobic metabolism
Citric acid cycle
the electrons derived from oxidation of nutrients
are passed to oxygen
Electron transport
Oxidative breakdown of nutrients | simpler to complex molecule
Catabolism
Reductive synthesis of biomolecules | complex to simpler molecule
Anabolism
Also called Krebs cycle or tricarboxylic acid cycle (TCA cycle)
Amphibolic
where does Amphibolic takes place?
mitochondria
it is oxidized and transferred to a sulfur atom of the reduced form of lipoamide
Hydroxyethyl group (HE)
it is reduced to dihydrolipoamide
Lipoamide
allosteric
enzyme that inhibited by NADH, ATP & succinyl-CoA
is citrate achiral and has no stereocenter: T or F
True
Oxidative decarboxylation of isocitrate to form a-ketoglutarate and CO2 is catalyzed by:
Isocitrate dehydrogenase
Oxidative decarboxylation of α-ketoglutarate to form succinyl-CoA is catalyzed by:
a-ketoglutarate
dehydrogenase complex
Thioester bond of succinyl-CoA is hydrolyzed to produce succinate and CoA-SH is catalyzed by:
succinyl-CoA synthetase
Hydration of fumarate to form L-malate is catalyzed by:
fumarase
Malate is oxidized to oxaloacetate, and another molecule of NAD reduced to NADH is catalyzed by:
malate dehydrogenase