Chapter 18 Quiz Flashcards
Which of the following changes is a transversion base substitution?
Cytosine to Guanine
Which of the following occur in expanding nucleotide repeats?
Hairpins in DNA
Mismatch repair in coli distinguishes between old and new strands of DNA on the basis of:
Methyl groups on the old strand
A polypeptide has the following amino acid sequence:
Met-Ser-Pro-Arg-Leu-Glu-Gly
The amino acid sequence of this polypeptide was determined in the series of mutants listed in parts a through e. For each mutant, indicate which one results in a nonsense mutation
Mutant 2: Met-Ser-Pro
Which of the following statements about an animal bearing a somatic mutation is TRUE?
The animal but not its offspring can be affected by the mutation.
Which of the following describes an intergenic suppressor mutation?
A mutation in gene A causes a mutant phenotype, then a mutation in gene B restores the original phenotype (where gene B acts as the intergenic suppressor mutation)
Which of the following statements regarding transitions and transversions are true? Select all that apply
Transitions are more common
Choose the correct statement(s) regarding amino acid mutations. Feel free to use the amino acid chart
Not An example of a missense mutation in a codon would be UCA to UAA
An example of a silent mutation in a codon would be UCA to UCG
A nucleotide substitution that changes the sequence of an mRNA codon, but not the amino acid specified is called a neutral mutation
A base substitution that changes the sequence and amino acid specified of an mRNA codon is called a missense mutation
Intragenic suppression is due to a second mutation within an already mutated gene that restores a wild-type phenotype
Choose the correct statement(s) regarding the following nucleotide sequence found on the template DNA strand. 3’ TAC CCG GTT ATA ACT5’.
NOT The mRNA sequence is 5’ AUG GGC CAA UAU UGA3’
Is 5 prime n or c terminus?
N
