Chapter 17- Male Pathology (Red Terms from Review Videos) Flashcards
abnormal urethral orifice on the ventral side of the penis (MC)
hypospadias
abnormal urethral orifice on the dorsal side of the penis (rare)
epispadias
95% of penile neoplasms are…
squamous cell carcinomas (SCC)
Risks for Penile Squamous Cell Carcinomas
uncircumcised, >40 years old, poor hygiene, developing countries, HPV-16 or -18, smoking
Signs/Symptoms of Penile Squamous Cell Carcinomas
abnormal texture, failure to heal
Increase in serous fluid in tunica vaginalis
hydrocele
_____ will result in elephantiasis
Filariasis
What percent of newborn males have cryptorchidism?
1%
10% are bilateral
Cryptorchidism can lead to _____ _____ by age 5-6 years; this will lead to sterility
testicular atrophy
Cryptorchidism will cause a 3-5x increase risk of ____ ____
testicular cancer
Inflammation of the epididymis is called…
epididymitis
Inflammation of the testis is called….
orchitis
Inflammation of the epididymis or testis commonly begin as…
UTI
These infections may cause testicular inflammation:
_____ (20%) or _____ (caseous granulomas)
Mumps (20% Orchitis in adult males)
TB
Signs/Symptoms of testicular torsion = spermatic cord twisting
severe engorgement, acute pain
Testicular torsion occurring in utero or perinatal
Neonatal torsion
MC Testicular torsion occurring between age 12-18
Adult torsion
Deformity leading to adult torsion
bell-clapper deformity
Testicular neoplasia MC between ages…
15-34 years old
Risks for testicular neoplasia
History of cryptorchidism in 10% of cases
Family history: brother (8-10x)
Caucasians, CA in contralateral testicle
Gonadal dysgenesis, androgen insensitivity
Malignant form of testicular neoplasia
Germ Cell Tumors (GCTs)
Types of germ cell tumors
- Seminoma
2. Nonseminomatous GCTs
Seminomas occur in the age range….
40-50 years
Seminomas are identifiable by…
lesions: well-demarcated
cells: uniform, round nuclei
Embryonal carcinoma (a type of Nonseminomatous GCTs) occur in the age range…
20-30 years
Yolk sac tumor (a type of nonseminomatous GCTs) occur at age…
3 years
Choriocarcinoma (a type of nonseminomatous CGTs) is identifiable by…
increase hCG
Teratoma (a type of nonseminomatous GCTs) occurs in the age range…
all ages
Embryonal carcinoma (a type of nonseminomatous GCTs) are identifiable by…
undifferentiated, indistinct borders
Features of testicular cancers are…
MC a painless testicular mass
Non-translucent
____ tend to be well-contained, possibly very large, and radiosensitive
Seminomas
_____ has earlier metastasis (via lymph and heme to liver and lungs), and is less likely palpable
Nonseminomatous GCTs