Chapter 17: Learning and Memory Flashcards

0
Q

What is nondeclarative memory?

A

Memories of “how”, shown by performance rather than recollection; skills such as riding a bike

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1
Q

What is declarative memory?

A

Memory of facts and information acquired through learning that can be stated and described

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2
Q

What are the two subtypes of declarative memory?

A

Semantic and episodic

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3
Q

What is semantic memory?

A

Generalized memory of facts

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4
Q

What are the three subtypes of nondeclarative learning?

A

Skill learning, priming, and conditioning

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5
Q

What is episodic memory?

A

Detailed autobiographical knowledge and memory of events

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6
Q

What is skill leaning?

A

Learning how to perform a task requiring motor coordination

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7
Q

What is priming?

A

The change of stimulus processing due to prior exposure to a stimulus

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8
Q

What are the three types of conditioning?

A

Classical conditioning, conditioned emotional response, and operant (instrumental) conditioning

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9
Q

What brain region is involved in classical conditioning?

A

Cerebellum

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10
Q

What brain region is involved in a conditioned emotional response?

A

Amygdala

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11
Q

What brain region is involved in operant (instrumental) conditioning?

A

Hippocampus

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12
Q

What brain region is involved in priming?

A

The frontal and occipitofrontal cortices

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13
Q

What brain region is involved in skill learning?

A

The basal ganglia

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14
Q

What bran region is involved in semantic memory?

A

Temporal cortex

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15
Q

What brain region is involved in episodic memory?

A

Frontal cortex

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16
Q

What is conditioning?

A

The association of two stimuli, or of a stimulus and a response

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17
Q

What are the two types of learning?

A

Associative and nonassociative

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18
Q

What is nonassociative learning?

A

A single stimulus presented once or repeated

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19
Q

What are the two subtypes of nonassociative learning?

A

Habituation and sensitization

21
Q

What is habituation?

A

A deceased response to repeated presentations of a stimulus

22
Q

What are the three aspects of memory systems?

A

Encoding, consolidation, and retrieval

23
Q

What happens in encoding?

A

Sensory information is captured and converted into a construct that can be stored within the brain

24
Q

What happens in consolidation?

A

Information that is encoded can be placed in long-term storage

25
Q

What happens in retrieval?

A

Stored information is recalled

26
Q

What is sensitization?

A

A prior strong stimulation increases response to most stimuli

27
Q

What causes Korsakoff’s syndrome?

A

Thiamine deficiency (which can be seen in chronic alcoholism)

28
Q

What brain region is damaged in Korsakoff’s syndrome?

A

Mammillary bodies of the thalamus

29
Q

What is Korsakoff’s syndrome?

A

A memory deficiency characterized by confabulation

30
Q

What is neuroplasticity?

A

The ability of the nervous system to change in response to experience

31
Q

Who first proposed the idea that synaptic alterations are the basis of learning?

A

Charles Sherrington (1897)

32
Q

What did Donald Hebb propose in 1949?

A

When a presynaptic and a postsynaptic neuron repeatedly fire together, the synaptic connection between the two becomes stronger and more stable

33
Q

What is Hebb’s postulate?

A

Cells that fire together, wire together.

34
Q

What is an engram?

A

A change in the brain that provides a physical basis for a memory (also called a memory trace)

35
Q

What is another name for non-declarative learning?

A

Procedural learning

36
Q

What was damaged in HM’s brain to cause memory loss?

A

A surgery that removed his hippocampus, amygdala, and some cortex

37
Q

What happened to HM after the surgery?

A

He had severe anterograde amnesia

38
Q

What did HM retain?

A

His past memories and some procedural learning

39
Q

What did we discover because of HM?

A

The existence of multiple memory systems

40
Q

What is reconsolidation?

A

The return of a memory trace to stable long-term storm, after recall

41
Q

What changes in short-term habituation?

A

Function

42
Q

What changes in long-term habituation?

A

Structure

43
Q

What is long-term potentiation (LTP)?

A

A persistent increase in the efficacy (strength) of synapses after a long stimulus

44
Q

Where was LTP first observed?

A

In Schaffer collaterals of the hippocampus

45
Q

How is CREB activated?

A

Activated during LTP induction by protein kinase and signaling

46
Q

What is CREB and what does it do?

A

Transcription factor that induce transcription of genes that change structure/function of neurons; CREB activation necessary for long-term memory

47
Q

Evidence 1 that LTP is a mechanism of memory formation:

A

The time course of LTP is the same as memory formation.

48
Q

Evidence 2 that LTP is a mechanism of memory formation:

A

Drug and genetic interventions that block/enhance LTP have similar function on learning and memory

49
Q

Evidence 3 that LTP is a mechanism of memory formation:

A

Learning a new task produces the same cellular changes that are produced by LTP.