Chapter 17: GIT-STOMACH Flashcards
Disorders of the stomach are a frequent cause of clinical disease, with inflammatory and
neoplastic lesions being particularly common.
In the United States, diseases related to gastric
acid account for nearly one third of all health care spending on GI disease.
In addition, despite
a decreasing incidence in certain locales such as the United States, gastric cancer remains a
leading cause of death worldwide.
The stomach is divided into four major anatomic regions:
- the cardia,
- fundus,
- body, and
- antrum.
The cardia and antrum are lined mainly by what?
by mucin-secreting foveolar cells that form small
glands.
antral glands are lined by
- mucin-secreting foveolar cells that form small glands similar in cardia and antrum
- but also contain endocrine cells,
- such as G cells, that release gastrin to stimulate luminal acid secretion by parietal cells within the gastric fundus and body.
The well-developed glands of the body and fundus also contain what?
chief cells that produce and secrete digestive enzymes such as pepsin.