Chapter 17: GIT- Congenital Abnorm- Pyloric Stenosis

Question 1

Congenital hypertrophic pyloric stenosis is mor?e common with

Answer 1

Congenital hypertrophic pyloric stenosis is three to four times more common in males and
occurs once in 300 to 900 live births.

Monozygotic twins have a high rate of corcordance,
suggesting a genetic basis.

Question 2

In Congenital hypertrophic pyloric stenosis family studies suggest a complex polygenic inheritance, which are the two chromosomal defect associated to this?

Answer 2

• Turner syndrome
• trisomy 18 ( Edward syndrome)

Question 3

Congenital hypertrophic pyloric

stenosis generally presents when?

Answer 3

second or third week of life as new-onset regurgitation and
persistent, projectile, nonbilious vomiting. Physical examination reveals hyperperistalsis and a
firm, ovoid abdominal mass. These findings stem from hyperplasia of the pyloric muscularis
propria, which obstructs the gastric outflow tract. Edema and inflammatory changes in the
mucosa and submucosa may aggravate the narrowing. Surgical splitting of the muscularis
(myotomy) is curative. Acquired pyloric stenosis occurs in adults as a consequence of antral
gastritis or peptic ulcers close to the pylorus. Carcinomas of the distal stomach and pancreas
may also narrow the pyloric channel due to fibrosis or malignant infiltration.

Question 4

What is revealed in the physical examination in Congenital Hypertrophic Pyloric Stenosis?

Answer 4

• hyperperistalsis and a
• firm, ovoid abdominal mass.

These findings stem from hyperplasia of the pyloric muscularis propria, which obstructs the gastric outflow tract.

Edema and inflammatory changes in the
mucosa and submucosa may aggravate the narrowing.

Question 5

What is the curative management for Congenital Hypertrophic Pyloric Stenosis?

Answer 5

• *Surgical splitting of the muscularis
  (myotomy) **is curative.

Question 6

Where does Acquired pyloric stenosis occurs?

Answer 6

in adults as a *consequence of antral
gastritis or peptic ulcers close to the pylorus.*

Carcinomas of the distal stomach and pancreas
may also narrow the pyloric channel due to fibrosis or malignant infiltration.