Chapter 17 (continued)

Question 1

A disorder characterized by uninhibited responses, lack of sustained attention, and hyperactivity.
Most common behavior disorder in childhood

Answer 1

ADHD

Question 2

a psychological reaction caused by the perception of aversive or threatening stimuli

Answer 2

stress response

Question 3

a general, imprecise term that can refer either to a stress response or to a situation that elicits a stress response

Answer 3

stress

Question 4

physiological reactions that prepare us for the strenuous efforts of fighting or fleeing

Answer 4

fight or flight response

Question 5

Hormone of the adrenal cortex that are important in protein and carbohydrate metabolism, secreted especially in times of stress.

Answer 5

glucocorticoid

Question 6

a hypothalamic hormone that stimulates the anteriour pituitary gland to secrete ACTH

Answer 6

CRH

Question 7

a hormone released by the anteriour pituitary gland in response to CRH; stimulates the adrenal cortex to produce glucocorticoids

Answer 7

ACTH

Question 8

a psychological caused by exposure to a situation of extreme danger and stress; symptoms include recurrent dreams or recollections; can interfere with social activities and cause a feeling of hopelessness

Answer 8

PTSD

Question 9

the pairing of the context/cue to the aversive stimuli

Answer 9

aquisition

Question 10

similiar to consolidation

• protein synthesis dependent
• second time window where you can interrupt a memory (memory = maluable)

Answer 10

reconsolidation

Question 11

• protein synthesis dependent

- laying down of a memory

Answer 11

consolidation

Question 12

serine/threonine protein kinase that regulates cell growth, cell mobility and protein synthesis

Answer 12

mTOR

Question 13

release of stress hormones

Answer 13

PVN secretes CRH
CRH activates anteriour pituitary secrete ATCH
ACTH atimulates adrenal cortex
Adrenal cortex releases cortisol (GLUC)

Question 14

animal models for anxiety

Answer 14

predator odor (emotional stress)
isolation stress (chronic - singly housed)
chroic unpredictable stress (submitted to stressor once a day for several days)
submersion stress
fear conditioning (most common - associate with shock, put in same context - no shock)
social defeat

Question 15

mTOR/reconsolidation/PTSD

Answer 15

give animal mTOR - reduction in memory
- blocking on reconsolidation
PTSD - give protein inhibitor (b/c reconsolidation is protein synthesis dependent) to interupt memory
can then try to delete fear component of memory.