Chapter 16 The Endocrine System Flashcards
Mechanisms of intercellular communication: via gap junctions; use ions, small solutes,and other lipid soluble materials as chemical mediators; effects are usually limited to adjacent cells of the same type that are interconnected by connexons
Direct communication
Works with or in harmony with the nervous system to control and coordinate all the activities of the body and maintain homeostasis
The endocrine system
Mechanisms of intercellular communication: Via extracellular fluids; use Paracrine factors as chemical mediator; effects are primarily limited to the local area where Paracrine factor concentrations are relatively high; target cells must have appropriate receptors
Paracrine Communication
Mechanisms of intercellular communication: via the bloodstream; use hormones as chemical mediators; effects are on target cells located in other tissues or organs; target cells must have an appropriate receptor
Endocrine communication
Via the synaptic cleft; use neurotransmitters as chemical mediators; effects are limited to very specific areas; target cells must have appropriate receptors
Neural communication
Are chemical messengers released by endocrine cells/glands into bloodstream to be transported throughout the body to regulate the metabolic functions and activities of other cells of the body
Hormones
Hormones; thyroxine, triiodothyronine, catecholamines(epinephrine), norepinephrine, dopamine, melatonin,
Amino acids derivatives
Chains of amino acids as polypeptide: ADH(antidiuretic hormone) 9 amino acids, and oxytocin 9 amino acids… Small proteins: insulin 51 amino acids, GH(growth hormone) 191 amino acids, and prolactin 198 amino acids… Glycoproteins: TSH(thyroid stimulating hormones), LH(luteinizing hormone), and FSH(follicle stimulating hormone)
Peptide hormones
Consist of carbon rings and side chains built either from fatty acids chains or cholesterol…
Lipid derivatives
Built from fatty acid chains and include leukotrienes and prostaglandins
Eicosanoids
None fatty acids chains (hydrophobic), built from cholesterol molecules and include testosterone, estrogen and progesterone, corticosteroids, and calcitriol
Steroid hormones
Physiological response causes a decrease in the release of the hormone most commonly used
Negative feedback
Physiological response causes a increase in the release of the hormone rarely used
Positive feedback
One hormone inhibits the response of another therefore they generate opposite responses; example: insulin lower blood sugar while glucagon raises blood sugar
Antagonistic effects
The two hormones generate the same effect and therefore the results is greater the effect that each would generate alone… Ex: ADH, aldosterone all raise blood pressure
Additive effects