Chapter 16: Pain, Temp, Sleep Flashcards
Specificity theory of pain
Pain and touch are carried on distinct pathways that project to different brain centers
Intensity of pain is related to the amount of associated tissue injury
Pattern theory of pain
Different sense organs have different levels of responsiveness to stimuli with different spatial and temporal profiles firing
Gate control theory of pain
Gate either opens or closes
Nociception
the processing of potentially harmful stimuli through a normally functioning nervous system
Nociceptors
Free nerve endings in afferent PNS that selectively respond to stimuli
A delta fibers
Lightly myelinated, medium, fast transmission
Reflex withdrawal due to pain or heat
Fast like delta force
C fibers
Smaller and unmyelinated
Slow, dull, aching pain poorly localized
A beta fibers
Large and myelinated
Touch and vibration
Pain transduction
Tissue is damaged; activation of nociceptors
Pain transmission
Conduction of pain impulses along A delta and C fibers into dorsal horn of spinal cord up to cortex for interpretation
Pain perception
Conscious awareness
Occurs in reticular and limbic and cerebral cortex
Pain modulation
Increase or decrease in transmission of pain signals
Segmental inhibition of pain
Rubbing an area that is injured
A beta fibers stimulated and impulses arrive at same spinal level as A delta or C fibers
Conditioned pain modulation
Pain is relieved when 2 noxious stimuli occur at the same time from different sites
Perceptual dominance
Pain at one site may mask another painful area
Nociceptive pain
Pain with normal tissue injury from known cause
Normal protective mechanism
Acute pain
Can last up to 3 months
Increased HR, BP, Sweating, dilated pupils, increased glucose
Chronic pain
More than 3-6 months
Out of proportion to any tissue injury
Hyperalgesia
increased sensitivity to pain
Allodynia
Pain due to normally nonpainful stimuli
Myofascial pain syndrome
Injury to muscle fascia and tendons
Compression of trigger point causes referred pain and becomes more generalized
Normal body temp
97.2-99.9
What mediates temperature primarily
Peripheral thermoreceptors in skin and abdominal organs
Chemical thermogenesis
Hypothalamus stimulates release of TSH from anterior pituitary, thyroxine released, adrenal medulla releases epinephrine, leads to vasoconstriction, glycolysis and increased metabolic rate
Body heat conservation
Hypothalamus stimulates SNS, which stimulates adrenal cortex, increased skeletal muscle tone and shivering and vasoconstriction keeps heat from escaping
Radiation
Heat loss through electromagnetic waves
Conduction
Direct molecule to molecule transfer
Convection
Through currents of gases or liquid
Mechanisms to lose heat
Vasodilation, hyperventilation, sweating
Aging and temperature
Slowed blood circulation, decreased shivering, decreased metabolic rate, decreased sweating
Decreased or no fever response to infection
Pathogenesis of fever
Pathogens produce endotoxins; production of prostaglandin E2 in periphery and brain; Increased temperature, B cell proliferation, increased catecholamines, vasoconstriction, shivering