chapter 16 cell division Flashcards
what is mitosis
form of nuclear division that produces daughter nuclei containing the same number of chromosomes as the parent cells = daughter cells are genetically identical to parent cells
– only occurs in cells with nuclei, but can be any cell
what occurs in interphase
→ cells carry out activities to prepare for mitosis - absorbing nutrients, building up protoplasm
→ chromosomes appear as chromatin (long thin threads)
→ centrioles divide in animal cells
→ DNA replication occurs: each chromatin thread replicates to form 2 identical chromatin threads - joined at centromere = sister chromatids → to ensure the chromosome number in parent cell is same as in the daughter cells
Eg 4 chromatin in parent cell = 4 pairs of sister chromatids (number of centromere = number of chromosomes)
what occurs in prophase
in picture: clump of cells
chromatin threads condense, coil and shorten (CCR) = become chromosome (1 pair of chromatin thread = 1 chromosome)
→ by end of prophase:
- nucleolus and nuclear envelope disappear
- 2 pairs of centrioles move to opposite ends of the cell
- asters form around centrioles
- Spindle forms with spindle fibres extending from 1 pole of the cell to the other
what occurs in metaphase
chromosomes line up along equatorial plane of spindle - centromere of each chromosome is attached on both sides to a spindle fibre
what occurs in anaphase
→ centromere divides (chromosomes are no longer connected = form chromatids) - spindle fibres shorten -> pull chromatids apart to opposite poles of cell
→ separated chromatids = form daughter chromosomes (eg 4 chromosomes = 8 chromatids with one centromere each = 8 daughter chromosomes)
what occurs in telophase
- Spindle fibres break down
- Nuclear envelope forms around daughter chromosomes at each pole = forms 1 nucleus at each pole (each nucleus has equal number of chromosomes)
- Nucleolus reforms in each nucleus
- Daughter chromosomes uncoil and lengthen = form thin chromatin threads (1 daughter chromosome = 1 chromatin thread)
what happens in cytokinesis
→ cleavage/furrows appear in cytoplasm between the 2 nuclei
→ furrows deepen = the 2 nuclei separate - produce 2 identical daughter cells
why is mitosis important
Mitosis enables growth of organism
→ mitosis produces new genetically identical cells for the organism to grow
Mitosis is needed for repair of worn out parts of the body
→ produces new cells that replace damaged cells
Mitosis allows asexual reproduction in plants to occur
→ grow daughter cells that are genetically identical to the parent cell
why must genetically identical daughter cells be produced
→ ensure that all daughter cells are genetically stable (genetically identical to parent cell) = all DNA is replicated for subsequent cell division/differentiation = future daughter cells are genetically identical
→ if error in DNA replication - new DNA strand formed (replicated) would be different from original = gene mutation in new daughter cell
→ gene mutation can cause abnormal proteins to be formed/uncontrolled division of cells - lead to excess cells that can form tumour (lead to cancer)
what is meiosis
→ a form of nuclear division that produces daughter nuclei containing half the number of chromosomes (haploid = n) as the parent nucleus (diploid = 2n)
→ occurs in gametes only (reproductive cells)
what happens in interphase (meiosis)
→ DNA replication: chromatin threads replicate - form 2 identical sister chromatids - 1 pair of sister chromatids attached at centromere (eg 4 chromatin threads = 8 sister chromatids = 4 pairs of sister chromatins = 8 chromosomes)
– each nucleus has (at least) 1 maternal chromatin and 1 paternal chromatin = after replication, forms 1 pair of maternal sister chromatids and 1 pair of paternal sister chromatids
→ pair of centrioles divide
what happens in prophase l
- each pair of sister chromatids go through CCR = become chromosomes (eg 1 pair of maternal sister chromatids = 1 pair of maternal chromosome)
- synapsis occurs: formation of homologous chromosome by pairing up - 1 paternal and 1 maternal chromosome pair up along whole length
- crossing over: non sister chromatids from each (maternal and paternal) homologous chromosome may break and exchange parts with each other = produces new combinations of genes along the chromosomes
- Homologous chromosomes repel each other
- Asters form around centrioles - centrioles move to opposite ends of cell
- Spindle fibres form
- Nuclear envelope and nucleolus disappear
what happens in metaphase l
→ pairs of homologous chromosomes arrange themselves along equatorial plane - two chromosomes of each pair face opposite poles of the cell
→ centromere of each chromosome is attached to a spindle fibre
what happens in anaphase l
- spindle fibres shorten = homologous chromosomes separate, pulled to opposite poles of cell
- chromosomes in the homologous chromosome do not separate into chromatids = one chromosome separates from the other chromosome (centromeres separate but do not divide - 1 homologous chromosome is made up of 2 chromosomes)
what happens in telophase l
→ nuclear envelope forms around chromosomes at each pole of the cell