Chapter 16 ( Breast )

Question 1

Breast is embryologically derived from ?

Answer 1

The skin

Question 2

The functional unit of the breast ?

Answer 2

The terminal duct lobular unit

Question 3

Before puberty breast tissue primarily consists of ?

Answer 3

Large ducts under the nipple

Question 4

Development of the breast after menarche ?

Answer 4

Lobules and small ducts form and are present in the highest density in the upper outer quadrant

Question 5

Galactorrhea is a symptom of breast cancer ?

Answer 5

No

Question 6

Commonest bacteria causing acute mastitis ?

Answer 6

Staphylococcus aureus

Question 7

Periductal mastitis is seen in ? Mechanism ? Presentation ?

Answer 7

Smokers
Relative vitamin A deficiency results in squamous metaplasia of lactiferous ducts producing duct blockage and inflammation

Presents as subareolar mass with NIPPLE RETRACTION

Question 8

Mammary duct ectasia is seen in ? Presentation ? Histology ?

Answer 8

Multiparous postmenopausal women

Presents as periareolar mass with green brown nipple discharge

Histology : chronic inflammation with plasma cells

Question 9

Most common change in premenopausal breast ?

Answer 9

Fibrocystic change

Question 10

Gross of fibrocystic change ?

Answer 10

Blue dome appearance

Question 11

Fibrocystic related changes and their risk for invasive carcinoma ?

Answer 11

1- fibrosis , cysts , APOCRINE METAPLASIA : no increased risk

2- ductal hyperplasia , sclerosing adenosis : 2x increased risk

3- Atypical hyperplasia : 5x increased risk

Question 12

Intraductal papilloma histology ?

Answer 12

Fibrovascular projections lined by epithelial and MYOEPITHELIAL cells

Question 13

Papillary carcinoma histology ?

Answer 13

Fibrovascular projections lined by epithelial cells WITHOUT MYOEPITHELIAL cells

Question 14

Fibroadenoma increased risk for carcinoma ?

Answer 14

No increased risk for carcinoma