chapter 16 Flashcards

1
Q

Dopamine (agonists)

A

Schizophrenia-like symptoms

Psychosis

Dyskinesias

Hallucinations

Delusions

Nausea

Vomiting

Addictive behaviors

Sexual function enhancement

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2
Q

Dopamine (antagonism)

A

Antipsychotic effect

Negative symptoms of schizophrenia

Temperature dysregulation

Antiemetic effect

Parkinsonism and extrapyramidal side effects (EPSEs)

Cognitive problems

Sexual dysfunction

Neuroendocrine dysregulation

Depression, anhedonia

Lack of energy, motivation

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3
Q

agonist

A

drugs that activate receptors

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4
Q

antagonists

A

drugs that block receptors

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5
Q

increased dopamine

A

schizophrenia

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6
Q

decrease in norepinephrine

A

depression

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7
Q

decrease in serotonin

A

depression

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8
Q

decrease in acetylcholine

A

alzheimer’s disease

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9
Q

Decrease in GABA

A

Anxiety

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10
Q

increase in glutamate

A

excitotoxicity leading to neuronal death

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11
Q

decrease in glutamate

A

psychotic thinking

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12
Q

serotonin (agonist)

A

Antidepressant effect

Anxiety

Migraine headaches

Nausea

Vomiting

Other GI disturbances

Sexual dysfunction

Decrease in penile erection capability

Reduced appetite and weight loss

Insomnia

Movement disorders

Temperature dysregulation

Psychotic thinking

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13
Q

serotonin (antagonist)

A

Depression

Dysthymia

Suicidality

Aggressiveness

Obsessive thinking

Sleep-wake cycle disruption

Pain

Compulsive behavior

Anxiety

Migraine headaches

Panic

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14
Q

acetylcholine (agonist)

A

Pupil contraction

Decreased heart rate

Constriction of bronchi

Increased respiratory secretions

Increased voiding

Salivation

Increased gastric secretions

Increased defecation

Sweating

Enhancement of cognitive processes

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15
Q

ACETYLCHOLINE (ANTAGONIST)

A

Dilated pupils

Increased heart rate

Dilation of bronchi

Decreased respiratory secretions

Decreased voiding

Dry mouth

Decreased gastric secretions

Constipation

Decreased sweating

Cognitive slowing

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16
Q

Norepinephrine (agonist)

A

Antidepressant effect

Vasoconstriction (alpha-1)

Increased heart rate (beta-1)

Bronchial dilation

Other physical effects

17
Q

NOREPINEPHRINE ANTAGONIST

A

Depressive effect

Vasodilation (alpha-1 antagonism)

Decreased heart rate (beta blocker)

Sexual dysfunction

Other physical effects