Chapter 16 Flashcards
Formin
nucleates assembly, remains on growing end
Arp 2/3
nucleates assembly of web structure
Thymosin
binds subunits, prevents assembly
Profilin
binds subunits, speeds elongation
Tropomodulin
prevents asembly and disassembly at minus ends
Tropomyosin
stabilizes filaments
Cofilin
binds ADP actin, accelerates disassembly
Gelsolin
severs filaments, binds to plus end
Capping Protein
prevents assembly and disassembly at plus end
Fimbrin
bundles close together (Actin)
alpha-actinin
bundles far away (Actin)
Filamen
binds actin at right angles
Spectrin
attaches actin to membrane
Beta end
GTP is bound to this end
gamma-TuRC
nucleates assembly, remains associated with minus end
Stathmin
binds subunits, prevents assembly
+TIPs
associates with plus end, links them to structures
XMAP215
associates with plus end, accelerates assembly
Kinesin 13
catastrophe and disassembly
Katanin
cuts microtubules
MAPs
stabilizes microtubules by bind along sides
Tau
binds microtubules close together
MAP2
binds microtubules far away
Plectin
links microtubules to intermediate filaments