Chapter 15 PowerPoint Flashcards
The autonomic nervous system is often associated with the ____ ____ ____ response
Fight or flight
What 7 things occur when the flight or flight response is activated?
Adrenaline is secreted into the circulatory system
Heart rate increases
Bronchi of lungs dilate
Pupils also dilate
Blood vessels dilate
Blood pressure increases
Sweat glands are activated
What are two divisions of the nervous system?
Somatic nervous system
Autonomic nervous system
What does the somatic nervous system control?
Skeletal muscle contraction
What 3 things does the autonomic nervous system control?
Controls cardiac muscle, smooth muscle, and glandular secretions
Which division of the nervous system is voluntary?
Somatic nervous system
Which division of the nervous system is involuntary?
The autonomic nervous system
What are the two division of the autonomic nervous system?
Sympathetic division and parasympathetic division
What response is associated with the sympathetic division?
Fight or flight response
What response is associated with the parasympathetic division?
Rest and digest response
What is another name for the sympathetic division?
Thoracolumbar division
What is another name for the parasympathetic division?
Craniosacral division
____ is a balance between the two divisions of the autonomic nervous system?
Homeostasis
What is an example of homeostasis in the autonomic nervous system? (circulatory system)
For eg., the heart is innervated by nerves from both systems to either speed up the heart (sympathetic) or slow it down (parasympathetic)
What occurs during activation of the sympathetic division of the ANS?
-What systems are activated?
-What prevents overheating?
-What system is deactivated?
Respiratory, cardiovascular and musculoskeletal systems are all activated to facilitate delivery of O2 and other nutrients to skeletal muscles
Sweating keeps the body from overheating during increased skeletal muscle usage
Blood flow to the digestive system is shunted since there are higher priorities at this moment
The sympathetic division is also known as the ____ ____ to reflect the origins of the spinal nerves?
Thoracolumbar system
The majority of ganglia of the sympathetic division belong to the ____ ____ ____ that run alongside the vertebral column?
Sympathetic chain ganglia
Thoracolumbar system?
Alternate name for the sympathetic division of the autonomic nervous system that is based on
the anatomical location of central neurons in the lateral horn of the thoracic and upper lumbar spinal cord
Sympathetic chain ganglia?
Series of ganglia adjacent to the vertebral column that receive input from central
sympathetic neurons
Ganglia vs nucleus/nuclei?
Bundle of neuron cell bodies found in the PNS vs bundle of cell bodies found in the CNS/brain
What are paravertebral ganglia?
Autonomic ganglia superior to the sympathetic chain ganglia
How many ganglia are on each side of the spinal cord per area/segment?
3 cervical
12 thoracic
4 lumbar
4 sacral
=23 total
The ____ and ____ levels of the sympathetic chain ganglia do not connect directly to the spinal cord via spinal roots?
Cervical and sacral
What is an effector?
A cell that performs a specific function in response to a stimulus
What are the three types of junctions within the sympathetic system?
a. Sympathetic nerve projects at same level as the target effector
b. If target is superior or inferior to the spinal segment
c. Associated with splanchnic nerves
White ramie communicantes?
Myelinated structures that provide a short connection
from a sympathetic chain ganglion to the spinal nerve that contains the preganglionic sympathetic fiber
(singular = ramus communicans)
Gray rami communicantes?
Unmyelinated structures that provide a short connection
from a sympathetic chain ganglion to the spinal nerve that contains the postganglionic sympathetic fiber
(singular = ramus communicans)
Superior cervical ganglion?
One of the paravertebral ganglia of the sympathetic system that projects to the head
Another name fore paravertebral ganglia?
AKA?
Autonomic ganglia superior to the sympathetic chain ganglia
Cervical ganglia
Collateral ganglia?
What?
Which 3?
Where situated?
Ganglia outside of the sympathetic chain that are targets of sympathetic preganglionic fibers
Celiac, inferior mesenteric, and superior mesenteric ganglia
Situated anterior to the vertebral column
What three ganglia are associated with splanchnic nerves?
Celiac ganglion
Superior mesenteric ganglion
Inferior mesenteric ganglion
Spinal nerve tracks up until it reaches the ____ ____ ____?
Superior cervical ganglion
Celiac ganglion?
One of the collateral ganglia of the sympathetic system that projects to the digestive system
Superior mesenteric ganglion?
One of the collateral ganglia of the sympathetic system that projects to the digestive
system
Inferior mesenteric ganglion?
One of the collateral ganglia of the sympathetic system that projects to the digestive
system
(Gonads/external genitalia)
What are the two types of synapses and what is released in each type?
Cholinergic – acetylcholine (ACh) is released
Adrenergic – norepinephrine (NE) is released
When thinking about cholinergic and adrenergic synapse, we need to consider both the ____ and the ____?
Agonist and the receptor
Agonist vs antagonist?
Agonist-any exogenous substance that binds to a receptor and produces a similar effect to the endogenous ligand
Antagonist-any exogenous substance that binds to a receptor and produces an opposing effect to the endogenous ligand
Ligand?
An atom or small molecule binds to another molecule resulting in the formation of a complex
Types of cholinergic receptors?
What do they bind to?
What do they activate?
Nicotinic receptors: binds to AChR (Acetylcholine receptor) to activate ligand-gated ion channel
Muscarinic receptors: binds to AChR (Acetylcholine receptor) to activate G protein-coupled receptor (GPCR)
How are cholinergic receptors named?
Named based on exogenous ligands (ie., nicotine and muscarine), ligands from outside of the body
Cholinergic receptors?
A synapse at which acetylcholine is released and binds to the nicotinic or muscarinic receptor
Nicotinic receptors?
A type of acetylcholine receptor protein that is characterized by also binding to nicotine and is an
ionotropic receptor
Muscarinic receptors?
A type of acetylcholine receptor protein that is characterized by also binding to muscarine and is a
metabotropic receptor
G protein-coupled receptor?
A membrane protein complex that consists of a receptor protein that binds to a signaling
molecule—a G protein—that is activated by that binding and in turn activates an effector protein (enzyme) that
creates a second-messenger molecule in the cytoplasm of the target cell
Exogenous ligands?
Ligands made outside the body such as nicotine and muscarine
What are the two types of adrenergic receptors?
What do they bind to?
What are there classes?
Alpha (α) adrenergic receptor: GPCR that binds norepinephrine; includes α1 and α2 classes
Beta (β) adrenergic receptor: GPCR that binds norepinephrine; includes β1, β2 and β3 classes
Another name for adrenaline?
Epinephrine
Another name for norepinephrine?
Noradrenaline
Alpha adrenergic receptors?
One of the receptors to which epinephrine and norepinephrine bind, which comes in
three subtypes: α1, α2, and α3