Chapter 15 exam 1 (d) Flashcards
T/F HIV is a bacteria infection
false it is viral
HIV is a ___ virus that causes immunosuppression
retrovirus
The viral infection of HIV causes the person to be susceptible to infections that would normally be controlled through___
body’s natural immune responses.
Retrovirus causes ___ making people susceptible to other infections
immunosuppresion
T/F most pts with HIV die from Aids
False most die to other infections
In north america, the prevalence of HIV has been highest amongest which populations?
- Men having sex with men
- people of color
- people who live in poverty
- adolescents
HIV remains a disease of marginalized individuals for example those that are disenfranchised by virtue of: (6)
- gender
- race
- sexual orientation
- poverty
- drug use
- lack of health care
What 3 areas have the US made strides in to produce longer life spans and lower death rates
- prevention
- testing
- treatment
HIV can only be transmitted under specific conditions that allow contact with ___
infected body fluids
name the body fluids that have been confirmed transmitted body fluids
- blood
- semen
- vaginal secretions
- breast milk
what is the most common mode of HIV transmission
sexual contact with an infected partner
what does sexual activity involve?
contact with semen, vaginal secretions, and or blood
How does contact with an infected sex partner give you HIV
it contains lymphocytes that cross from them to you in the infected fluid
During sex who is most likely to get the infection?
the receiver
Why is the receiver during sex most likely to contract HIV?
because they have prolonged contact with infected fluids
who is more likely to get HIV: the hetrosexual woman with herpes (active) or the Hetrosexual male that performs anal
the woman. the likely hood of contracting the disease goes up if the presence of other STIs are present.
What is the most common work related HIV transmission
puncture wounds
Perinatal transmission can occur during (3)
- pregnancy
- delivery
- breastfeeding
List 5 modes of transmission that HIV is NOT spread by
- hugging
- dry kissing
- shaking hands
- sharing eating utensils
- toilet seats
transmission of HIV is subject to the same requirements as other microbes those are
- large enough amount of the virus must enter the body of a host
What are some variables that influence whether infection will be established after an exposure``
- duration and frequency of contact with the organism
- volume, virulence, and concentration of the organism
- host immune status
What type of virus is HIV
Ribonucleic acid virus
why is HIV called a retrovirus
because it replicates in a ĥbackward manner
How does the HIV virus enter the cell
binds to the specific CD4 and chemokine receptors
what cell does the HIV virus enter
CD4+T cell
HIV is a ribonucleic acid virus which replicates using its RNA template to produce _ which is then integrated into the cell
DNA
damage and destruction is caused by immune dysfunction in HIV by damaging and destroying ____ and _____
T helper cells and CD4+T lymhocytes
Viral RNA enters the cell, produces viral __in the presence of reverse transcriptase, and incorporates itself into the ___ ___ in the prescence of integrase, causing permanent ___ ___ and the production of new ___
dna
human genome
cellular infection
virons
The production of new virons causes two actions:
- because all genetic material is replicated during cell division, all daughter cells will be infected
- viral DNA in the genome will direct the cell to make new hiv
new viral RNA develops in long strands that are cut in the presence of ___
protease
the cut viral RNA leaves the cell through what process
the budding process
define viremia
large viral levels in the blood
5 cells that can be infected with the HIV virus
- cd4+t cells
- lymphocytes
- monocytes/macrophages
- astrocytes
- oligodendrocytes
how long does the initial infiection with HIV that results in viremia last
few weeks
normal lab value for CD4+T cell count
800 to 1200 cells/ul
immune problems start to happen when CD4+T cell count drop to __
<500 cells /ul
Severe problems develop when CD4+t cells reach _
2oo cells /ul
if you have an insufficient immune response what happens
opportunistic disease will take over
4 stages of HIV infection
- acute
- asymptomatic
- symptomatic
- aids
when HIV specific antibodies develop .. is what stage
acute
During acute stage ____ like syndrome that may be mistaken for teh flue
mononucleosis
when does he symptoms of actue generally occur
2 to 4 weeks after the intial infetion
in acute stage how long does the symptoms generally last
1 to 2weeks although some symptoms may last months
during the acute phase some people develop neurologic complications such as (4)
- aseptic meningitis
- peripheral neuropathy
- facial palsy
- guillain-barre syndrome