Chapter 14: RBC Flashcards

1
Q

Most specific Morphologic finding

A

Hereditary Spherocytosis

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2
Q

Most important enzyme derangement

A

G6PD

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3
Q

Most common trigger of episodic Hemolysis Infections

A

Infections

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4
Q

Most commonly involved sites of Sickle cell disease

A

Bones, lungs, liver, brain, spleen, and penis

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5
Q

Most common cause of patient morbidity and mortality in Sickle cell disease

A

Occlusive crises

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6
Q

Most common cause of β+ Thalassemia

A

Splicing mutations

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7
Q

Most common cause of β0 Thalassemia

A

Chain terminator mutation

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8
Q

Most severe form of α-Thalassemia

A

Hydrops fetalis

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9
Q

Most common form of immunohemolyticanemia

A

Warm Antibody Type

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10
Q

Most cases are seen in children following viral infections

A

Cold Hemolysin Type

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11
Q

Most commonly seen with DIC

A

Microangiopathic HemolyticAnemia

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12
Q

Most common and important anemias associated with red cell underproduction

A

Nutritional deficiencies

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13
Q

Most important molecules whose synthesis is dependent on folates

A

dTMP

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14
Q

Most ferritin is stored in the parenchymal cells Liver

A

Liver

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15
Q

Most iron stored in

A

Hemosiderin

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16
Q

Most common cause of Iron Deficiency

A

Chronic Blood Loss

17
Q

Most common cause of Myelopthisic Anemia

A

Metastatic Cancer

18
Q

Most common cause of Primary Polycythemia

A

Polycythemia vera

19
Q

Most feared site for hemorrhages

A

Intracranial

20
Q

Bleeding most commonly implicated are quinine, quinidine, and vancomycin

A

Drug-Induced Thrombocytopenia

21
Q

One of the most common hematologic manifestation of HIV infection

A

HIV-associated Thrombocytopenia

22
Q

Most likely results from a direct platelet-aggregating effect of Heparin

A

Type I thrombocytopenia

23
Q

Most common and important inherited deficiencies of coagulation factors affect

A

Factor VIII and Factor IX hemophilia

24
Q

The two most common inherited disorders of bleeding

A

Factor VIII-vWF Complex

25
Q

Most common inherited bleeding disorder of humans

A

Von Willebrand Disease

26
Q

Most common presenting symptoms of Von Willebrand disease

A

Bleeding from Mucous membrane

27
Q

Most common hereditary disease associated with life threatening bleeding

A

Hemophilia A (Factor VIII deficiency)

28
Q

Most often in Iron Deficiency

A

Microcytic Hypochromic Anemias