Chapter 14: RBC Flashcards
Most specific Morphologic finding
Hereditary Spherocytosis
Most important enzyme derangement
G6PD
Most common trigger of episodic Hemolysis Infections
Infections
Most commonly involved sites of Sickle cell disease
Bones, lungs, liver, brain, spleen, and penis
Most common cause of patient morbidity and mortality in Sickle cell disease
Occlusive crises
Most common cause of β+ Thalassemia
Splicing mutations
Most common cause of β0 Thalassemia
Chain terminator mutation
Most severe form of α-Thalassemia
Hydrops fetalis
Most common form of immunohemolyticanemia
Warm Antibody Type
Most cases are seen in children following viral infections
Cold Hemolysin Type
Most commonly seen with DIC
Microangiopathic HemolyticAnemia
Most common and important anemias associated with red cell underproduction
Nutritional deficiencies
Most important molecules whose synthesis is dependent on folates
dTMP
Most ferritin is stored in the parenchymal cells Liver
Liver
Most iron stored in
Hemosiderin
Most common cause of Iron Deficiency
Chronic Blood Loss
Most common cause of Myelopthisic Anemia
Metastatic Cancer
Most common cause of Primary Polycythemia
Polycythemia vera
Most feared site for hemorrhages
Intracranial
Bleeding most commonly implicated are quinine, quinidine, and vancomycin
Drug-Induced Thrombocytopenia
One of the most common hematologic manifestation of HIV infection
HIV-associated Thrombocytopenia
Most likely results from a direct platelet-aggregating effect of Heparin
Type I thrombocytopenia
Most common and important inherited deficiencies of coagulation factors affect
Factor VIII and Factor IX hemophilia
The two most common inherited disorders of bleeding
Factor VIII-vWF Complex
Most common inherited bleeding disorder of humans
Von Willebrand Disease
Most common presenting symptoms of Von Willebrand disease
Bleeding from Mucous membrane
Most common hereditary disease associated with life threatening bleeding
Hemophilia A (Factor VIII deficiency)
Most often in Iron Deficiency
Microcytic Hypochromic Anemias
