Chapter 14 Quiz - Inflammation & Tissue Repair

Question 1

Edema, pain, and loss of function occur due to increased capillary permeability.

True or false?

Answer 1

True

Question 2

The inflammatory response is stereotypical.

True or false?

Answer 2

True

Question 3

Prostaglandins and leukotrienes are examples of liver acute phase proteins.

True or false?

Answer 3

False

Question 4

Granulomatous inflammation is an example of acute inflammation.

True or false?

Answer 4

False

Question 5

Pyrexia is another term for a pressure sore.

True or false?

Answer 5

False

Question 6

Stroma refers to the structural cells of an organ, e.g., connective tissues.

True or false?

Answer 6

True

Question 7

Inflammation is the first stage of wound healing.

True or false?

Answer 7

True

Question 8

Granulation tissue is noted in the wound; this is a sign of infection and poor wound healing.

True or false?

Answer 8

False

Question 9

Wounds that heal by secondary intention will most likely scar.

True or false?

Answer 9

True

Question 10

___?___ is the term for a protein-rich fluid leaving blood vessels.

Answer 10

___Exudate___ is the term for a protein-rich fluid leaving blood vessels.

Question 11

The ___?___ stage and the ___?___stage are the 2 stages of acute inflammation.

Answer 11

The ___vascular___ stage and the ___cellular___stage are the 2 stages of acute inflammation.

Question 12

The 2 types of cells that release histamine are:

___?___ and ___?___

Answer 12

basophils and mast cells

Question 13

___?___ is the term for the functional cells of an organ.

Answer 13

___Parenchyma___ is the term for the functional cells of an organ.

Question 14

___?___ are bands of scar tissue joining 2 surfaces that are normally separated.

Answer 14

___Adhesions___ are bands of scar tissue joining 2 surfaces that are normally separated.

Question 15

CRP and ESR are lab tests orderd on a patient. The physician probably suspects:

1. infections disease
2. inflammatory disease
3. venereal disease
4. fever

Answer 15

2. inflammatory disease

Question 16

Select ALL of the signs and symptoms below that you would expect to see in a patient with a chronic inflammatory disease. There can be more than one correct answer.

1. Skeletal muscle catabolism (cachexis/wasting)
2. Leukocytosis (occ. Leukopenia)
3. Lymphadenopathy
4. Fever, anorexia, malaise, lethargy & somnolence

Answer 16

ALL

1. Skeletal muscle catabolism (cachexis/wasting)
2. Leukocytosis (occ. Leukopenia)
3. Lymphadenopathy
4. Fever, anorexia, malaise, lethargy & somnolence

Question 17

Which of the following would NOT be something you would recommend to your patient who is suffering with a chronic inflammatory disease?

1. Increase your ratio of ω-6: ω-3 fatty acids by eating:
   - more corn oil, sunflower oil/seeds, safflower oil and
   - less fatty fish, fish-oil supplements, EPA and DHA, walnuts, flaxseed
2. Use anti-inflammatory medications such as aspirin, NSAIDs
3. Decrease stress (e.g. with increase exercise)
4. Follow a low-glycemic index, low-calorie diet

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Increase DECREASE your ratio of ω-6: ω-3 fatty acids by eating:

more LESS corn oil, sunflower oil/seeds, safflower oil and
less MORE fatty fish, fish-oil supplements, EPA and DHA, walnuts, flaxseed

Answer 17

1. Increase your ratio of ω-6: ω-3 fatty acids by eating:
   - more corn oil, sunflower oil/seeds, safflower oil and
   - less fatty fish, fish-oil supplements, EPA and DHA, walnuts, flaxseed

You would want to :

• DECREASE your ratio of ω-6: ω-3 fatty acids by eating:
• LESS corn oil, sunflower oil/seeds, safflower oil and
• MORE fatty fish, fish-oil supplements, EPA and DHA, walnuts, flaxseed

Question 18

Pressure (e.g. laying on a bony prominence), shearing forces (e.g. pulling a person up in bed), friction (e.g. using one’s elbows to get up from bed), and overly-dry skin (e.g. if dehydrated) are all factors that can contribute to the formation of decubitus ulcers.

True or false?

Answer 18

False

Moisture (e.g. from urine/feces, sweat, wound drainage) is the last contributing factor.

Question 19

Your post-operative patient has a temperature of 101º F. It would be reasonable to hypothesize that a post-op infection may be the PATHOphysiologic cause of her pyrexia as you know that fever is caused by pyrogens secreted by WBCs and tissue cells at wound sites. Pyrogens cause the hypothalamus to re-set the body temperature to a higher level so you would not be surprised to see her shiver as her body ‘tries’ to get to this new, higher set-point.

True or false?

Answer 19

True

Question 20

Which of the following is NOT an acute phase protein or other protein that is a PLASMA-derived mediator of inflammation?

1. Complement
2. Fibrinogen and C-reactive peptide (CRP)
3. IL-1 and IL-6
4. Kinins

Answer 20

3. IL-1 and IL-6

Question 21

Which of the following are cell-derived mediators of inflammation? Select ALL that apply.

1. Leukotrienes
2. PAF - platelet activating factor
3. Prostaglandins
4. Histamine

Answer 21

ALL

1. Leukotrienes
2. PAF - platelet activating factor
3. Prostaglandins
4. Histamine