Chapter 14 - Important Slides Part 2

Question 1

What are interferons and interleukins?

Answer 1

Cytokines, secreted by cytotoxic T cells. Help other cells to destroy antigens.

Question 2

What are Suppressor T cells (regulatory T cells or Tregs)?

Answer 2

They inhibit B and T cells and prevent them from attacking the body’s own good cells.

Question 3

What are dendritic cells?

Answer 3

1. Macrophages
2. Recognizes and digest foreign antigens
3. They present antigens on the surface to stimulate B and T cells

Question 4

How are dendritic cells used for immunotherapy? (!!!)

Answer 4

Cultured and exposed outside the body and reinfused into the body and get them to stimulate T and B cells.

Question 5

How are monoclonal antibodies (MoAb) used in immunotherapy? (!!!)

Answer 5

These are antibodies created in a lab by cloning technique; multiple copies of cells and genes that kill tumor cells; passive immunotherapy.

Question 6

How are vaccines used in immunotherapy?

Answer 6

Contains antigens from the patient’s tumor cells; when injected they stimulate patient’s own T cells to recognize and kill cancerous cells; active immunotherapy.

Question 7

How does donor lymphocyte infusion provide immunotherapy? (!!!)

Answer 7

After bone marrow transplant, T cells from donor can replace a patient’s system and attack tumor; passive immunotherapy.

Question 8

What is IgG?

Answer 8

Can cross through the placenta to provide immunity for newborn

Question 9

What is IgE?

Answer 9

Important for allergic reaction and fighting parasitic infections

Question 10

What is IgA?

Answer 10

Primarily secreted across digestive tract into stomach and intestines

Question 11

What is IgD?

Answer 11

Helps develop B lymphocytes into plasma and memory cells.

Question 12

What type of immunity is affected by HIV?

Answer 12

HIV destroys helper T cells (CD4+)