Chapter 14/15 - Patterns of Inheritance Flashcards

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1
Q

The passing of traits from parents to offspring through asexual or sexual reproduction

A

Heredity

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2
Q

Heredity by means of genes assumed

A

traits were from ‘fluid’ like blood

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3
Q

The first investigator to achieve and document successful experimental hybridizations, or the mating of unlike parents

A

Josef Klreuter

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4
Q

Who in 1760 cross-fertilized (or crossed, for short) different strains of tobacco and obtained fertile offspring?

A

Josef Klreuter

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5
Q

By cross-fertilizing (or crossed, for short) different strains of tobacco Josef Klreuter produced __________

A

hybrids

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6
Q

Who observed variations different from parent

plants

A

Josef Klreuter

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7
Q

Josef Klreuter:

Hybrid offspring crosses resulted in ___________________________________

A

even more differences compared to the grandparents and parent plants

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8
Q

Who crossed garden pea plants that had either yellow or green seeds (true-breeding)?

What did this result in?

A

T.A. Knight (1823)

Hybrids produced yellow or	
green seeds (segregating)
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9
Q

Offspring produced from self-fertilization, remaining uniform from one generation to the next.

A

true breeding

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10
Q

Some offspring exhibit one form of a trait (yellow seeds), and other offspring from the same mating exhibit a different form (green seeds).

A

segregating

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11
Q

Was a scientist, friar and abbot

Grew up on a farm

Math and physics background allowed him to approach genetics from a mathematical standpoint

A

Gregor (Johann) Mendel

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12
Q

Mendel studied __________________________

A

hybrid crosses in pea plants

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13
Q

What characteristics did Mendel find easily distinguishable in pea plants?

A

shape of seeds

color of seeds

color of pods

shape of pods

plant height

position of flowers

flower color

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14
Q

Mendel studied hybrid crosses in pea plants due to ___________________________________

A

Due to true-breeding, pure varieties of each trait were available

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15
Q

Mendel studied hybrid crosses in pea plants because pea plants are _______________________

A

small and grow fast

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16
Q

While studying pea plants Mendel discovered that male and female parts on the same flower of the plant, allow for ____________________________

A

self-fertilization (retention of trait)

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17
Q

Mendel usually conducted his experiments in three stages: Which were?

A
  1. Mendel allowed plants of a given variety to self-cross for multiple generations to assure himself that the traits he was studying were indeed true-breeding—that is, transmitted unchanged from generation to generation
  2. performed crosses between true-breeding varieties exhibiting alternative forms of traits. He also performed reciprocal crosses: using pollen from a whiteflowered plant to fertilize a purple-flowered plant, then using pollen from a purple-flowered plant to fertilize a white-flowered plant.

3.Finally, Mendel permitted the hybrid offspring produced by these crosses to self-fertilize for several generations, allowing him to observe the inheritance of alternative forms of a trait. Most important, he counted the numbers of offspring exhibiting each trait in each succeeding generation.
.

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18
Q

concepts of inheritance in which traits of parents were carried by fluid and “blended” in offspring.

A

blending inheritance,

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19
Q

A cross that follows only two variations on a single trait, such as white- and purple-colored flowers. This deceptively simple kind of cross can lead to important conclusions about the nature of inheritance.

A

monohybrid cross

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20
Q

One trait, two variations

A

monohybrid cross

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21
Q

exhibits only one of two traits with no blending

A

F1 generation

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22
Q

When Mendel crossed white-flowered and purple-flowered plants, the hybrid offspring he observed did not have flowers of intermediate color, as the hypothesis of blending inheritance would predict. Instead, in every case the flower color of the offspring resembled that of one of their parents. These offspring are customarily referred to as the ______________________

A

first filial generation, or F1

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23
Q

No blending of traits

Always inherit same trait as one parent

A

first filial generation, or F1

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24
Q

In a cross of white-flowered and purple-flowered plants, the F1 offspring all had _________ flowers.

Mendel called these flowers the ___________ trait.

A

purple

purple; dominant

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25
Q

In Mendels experiment, what color flowers were referred to as the recessive trait

A

white

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26
Q

Mendel referred to the form of each trait expressed in the F1 plants as ________________ and to the alternative form that was not expressed in the F1 plants as _________________

A

dominant

recessive

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27
Q

exhibits a 3:1 ratio of both traits

A

F2 generation

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28
Q

After allowing individual F1 plants to mature and self-fertilize, Mendel collected and planted the seeds from each plant to see what the offspring in the ________________ generation would look like.

A

second filial generation, or F2,

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29
Q

What generation are offspring?

A

second filial generation, or F2,

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30
Q

What did Mendel find in the second filial generation, or F2?

A

Predominantly purple flower(75%) with reappearance of recessive white flowers (25%) , whom was hidden in F1 generation.

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31
Q

the dominant-to-recessive ratio among the F2 plants was always close to _________

A

3:1; or 1:2:1

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32
Q

1 true-breeding dominant: 2 not-true-breeding dominant: and 1 true-breeding recessive.

A

ratio of F2 plants

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33
Q

ratio of F2 plants

A

1 true-breeding dominant: 2 not-true-breeding dominant: and 1 true-breeding recessive.

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34
Q

Mendel performed crosses (Parents, then F1)
for all 7 traits in pea plants
– Found similar results. Describe his results___________________________

A

75% possessed dominant trait

25% possessed recessive trait

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35
Q

Further experiments by Mendel revealed that the
recessive trait was always
_____________________, F3, F4, F5 generations
always had __________flowers

A

true-breeding

white

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36
Q

⅓ of the dominant, purple-flowered F2 individuals were ________________, ____ were not.

A

true breeding

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37
Q

Mendel’s Principle of Segregation explains ___________________

A

monohybrid observations

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38
Q

Mendels Conclusions:

A
  1. plants he crossed did not produce progeny of intermediate appearance
  2. For each pair of alternative forms of a trait, one alternative was not expressed in the F1 hybrids, although it reappeared in some F2 individuals. The trait that “disappeared” must therefore be latent (present but not expressed) in the F1 individuals.
  3. The pairs of alternative traits examined were segregated among the progeny of a particular cross, some individuals exhibiting one trait and some the other.
  4. These alternative traits were expressed in the F2 generation in the ratio of ¾ dominant to ¼ recessive. This characteristic 3:1 segregation is referred to as the Mendelian ratio for a monohybrid cross.
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39
Q

Principle of Segregation

A

plants crossed did not produce progeny of intermediate appearance

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40
Q

These alternative traits were expressed in the F2 generation in the ratio of ¾ dominant to ¼ recessive. This characteristic 3:1 segregation is referred to as the _______________ for a monohybrid cross.

A

Mendelian ratio

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41
Q

Modern day description of Mendel’s findings:

Parents pass their physiological traits to their offspring via ____________ , individual receives _____copy of each _______ from each parent

A

genes
one
gene

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42
Q

Modern day description of Mendel’s findings:

Not all copies of a gene are___________

The alternative forms of a gene are called_________

When two haploid gametes containing the same allele fuse during fertilization, the resulting offspring is said to be _____________

When the two haploid gametes contain different alleles, the resulting offspring is said to be __________

A

identical

alleles

homozygous

heterozygous

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43
Q

Modern day description of Mendel’s findings:

The two alleles remain discrete—they neither _____ with nor _____ each other. Therefore, when the individual matures and produces its own gametes, the alleles ________________________

A

blend; alter

segregate randomly into these gametes (offspring)

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44
Q

Modern day description of Mendel’s findings:

In all individuals, only ____ allele is expressed
dominant) and the other is unexpressed (recessive

A

one

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45
Q

Modern day description of Mendel’s findings:

The total set of alleles that an individual contains is called ______________

The physical appearance or other observable characteristics of that individual, which result from an allele’s expression, is termed _______________

the _________ is the blueprint, and the _________ is the visible outcome in an individual.

A

genotype

phenotype

genotype

phenotype

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46
Q

What process is this?

Alternative alleles for a character segregate from each other during gamete formation and remain distinct

A

Principle of Segregation

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47
Q

Mendel’s first law of heredity

A

Principle of Segregation

48
Q

What process is this?

The two alleles for a gene segregate during gamete formation and are rejoined at random, one from each parent, during fertilization.

A

Principle of Segregation

49
Q

The physical basis for allele segregation is the behavior of ___________ during ________. Homologues for each chromosome disjoin during _________ of ________. The second meiotic division then produces _________ that contain only _____ homologue for each chromosome.

A

chromosomes

meiosis

anaphase 1; meiosis

gametes

one

50
Q

Mendelian ratio of 3:1 is actually a ratio of ___________

A

1:2:1

1 Homozygous dominant : 2 heterozygous : 1 homozygous recessive

51
Q

allows symbolic analysis

A

Punnett square

52
Q

allows simplistic calculation and representation of crosses

A

Punnett square

53
Q

IN a punnet square the UPPER CASE LETTER represents ________

LOWER CASE LETTER REPRESENTS _________

A

dominant trait

recessive trait

54
Q

Genotype of a true-breeding purple-flowered individual would be designated _______.

Genotype of an individual that is true-breeding for the recessive white-flowered trait would be designated ____

A

PP

pp

55
Q

Those that _____________ possess dominant traits would have one or two capital letters (PP or Pp)

A

phenotypically

56
Q

____________, dominant

traits are expressed as homozygous dominant (PP) or heterozygous (Pp)

A

Genotypically

57
Q

________________ are genotypically homozygous

recessive (pp) and phenotypically exhibit the recessive trait

A

recessive traits

58
Q

We use __________ to visually calculate the probability of offspring having a specific genotype or phenotype

Data from experiments vs.
Calculated heredity

A

Punnett squares

59
Q

White-flowered parent (pp) can produce only ________

True-breeding purple-flowered parent (PP, homozygous dominant) can produce only________

The union of these gametes can produce only _____________ offspring in the F1 generation

The phenotypic ratio is 3 purple: 1 white. The genotypic ratio is _____________

A

p gametes

P gametes

heterozygous Pp

1PP:2Pp:1pp.

60
Q

2 probability rules help predict monohybrid cross results : these rules include

___________________, ___________________

A
  1. Two events are mutually exclusive if both cannot happen at the same time.
  2. The event is independent
61
Q

a breeding experiment between P generation (parental generation) organisms that differ in a single given trait. The P generation organisms are homozygous for the given trait, however each parent possesses different alleles for that particular trait.

Round Rr) vs Wrinkled (Rr)

A

monohybrid cross

62
Q

Round Rr) vs Wrinkled (Rr) is an example of what experiment?

A

monohybrid cross

63
Q

What are the possible combinations of alleles?

A

RR: 1/4

Rr: 1/2

Rr: 1/4

64
Q

states that the probability of two independent events both occurring is the product of their individual probabilities.

A

rule of multiplication

Consider the purple F1 parents. They are all Pp (heterozygotes), so the probability that a particular F2 individual will be pp (homozygous recessive) is the probability of receiving a p gamete from the male (½) times the probability of receiving a p gamete from the female (½), or ¼:

65
Q

What rule is this?

The probability of receiving a p gamete from the male (½) X the probability of receiving a p gamete from the female (½) = ¼:

A

rule of multiplication

Mom: ½ X Dad: ½ = (For genotype) RR: ¼

66
Q

What rule is this?

To apply this to our cross of heterozygous purple F1, FOUR mutually exclusive outcomes are possible: PP, Pp, pP, and pp. The probability of being heterozygous is the same as the probability of being either Pp or pP, or ¼ plus ¼, or ½:

A

The rule of addition

Mom: ½ X Dad: ½ = (For genotype) Rr: ¼ + ¼ = 2/4 = ½

67
Q

The probability of either of two different numbers is the sum of the individual probabilities, or restated as the

A

The rule of addition

68
Q

T/F
Humans possess several dominant and recessive traits

Genetics studies crosses already performed or, ___________ history

A

true

family

69
Q

A consistent graphical representation of matings and offspring over multiple generations for a particular trait.

Used by genetics

A

pedigree

70
Q

A pedigree can form _____________________

A

models of inheritance

71
Q

A dominant pedigree, traced the inheritance of a form of blindness caused by a dominant allele called

A

Juvenile glaucoma

72
Q

A form of an allele causes this disease in children that eventually leads to blindness

A

Juvenile glaucoma

73
Q

What disease was this?

Pedigree of all matings determined the
original carrier of the allele who died in 1495, France

Since the trait shows up frequently in every generation, geneticists deduced this allele is the dominant form

A

Juvenile glaucoma

74
Q

Follows the behavior of two different traits in a single cross

A

dihybrid cross

75
Q

A single genetic cross involving two different traits, such as flower color and plant height.

A

dihybrid cross

76
Q

Mendels next question was?

A

Do different traits behave independently in hybrids

77
Q

Mendels next question: Do different traits behave independently in hybrids

What is the name of this experiment?

First established a series of true-breeding lines of peas that differed in two of the seven characters he had studied

He then crossed contrasting pairs of the true-breeding lines to create heterozygotes. These heterozygotes are now doubly heterozygous, or dihybrid

Finally, he self-crossed the dihybrid F1 plants to produce an F2 generation, and counted all progeny types.

A

Mendel’s dihybrid cross in pea plants

– Example cross:
• Pea shape: Round (R) or wrinkled (r)
• Pea color: Yellow (Y) or green (y)
• The dihybrid cross between two true-breeding plants:
– Dominant: Round (RR) and Yellow (YY)
– Recessive: Wrinkled (rr) and green (yy)

If all genes act independently, then there can only be four possible phenotypic combinations

  • Round Yellow (RRYY, RrYy)
  • Round Green (RRyy, Rryy)
  • Wrinkled Yellow (rrYy, rrYY)
  • Wrinkled Green (rryy)
78
Q

What did Mendel actually observe? From a total of 556 seeds from self-fertilized dihybrid plants, he observed the following results:

A

315 round yellow (signified R____ Y____, where the underscore indicates the presence of either allele),
108 round green (R____ yy),
101 wrinkled yellow (rr Y____), and
32 wrinkled green (rr yy).

These results are very close to a 9:3:3:1 ratio. (The expected 9:3:3:1 ratio for 556 offspring is 313:104:104:35.)

79
Q

Mendel’s second law of heredity

A

Principle of Independent Assortment

80
Q

What law is this?

In a dihybrid cross, the alleles of each gene assort
independently

A

Principle of Independent Assortment

81
Q

What law is this?

The segregation of different allele pairs is independent

A

Principle of Independent Assortment

82
Q

In a ___________, an individual with unknown genotype is crossed with the homozygous recessive genotype—that is, the recessive parental variety.

A

testcross

83
Q

How did Mendel continue to test his hypothesis and model?

A

testcross

84
Q

To test his model further, Mendel devised a simple and powerful procedure called the

A

testcross

85
Q

Crosses the unknown with a known and determines ratios of offspring

A

testcross

86
Q

Example cross: Purple (PP or Pp) and White (pp) flowers

Cross unknown with ______

If cross results in any ________ flowered offspring, then that suggests unknown parent is__________

A

White (pp)

white

heterozygous

87
Q

Mendel used test-crosses to determine

A

the genotype of his F2 generation plants

88
Q

used to determine the genotype of an individual when two genes are involved

A

testcrosses

89
Q

Describes a mode of inheritance in which more than one gene affects a trait, such as height in human beings; polygenic inheritance may produce a continuous range of phenotypic values, rather than discrete either–or values.
.

A

polygenic inheritance

90
Q

What is this describing?

More than one gene is involved in producing a trait.
Produces traits that have a continuous range rather than two independent values.

Ex: Height in pea plant vs height in humans

A

polygenic inheritance

91
Q

Most __________ have contributions from

several _______, resulting in the range

A

phenotypes

genes

92
Q

Variation in a trait that occurs along a continuum, such as the trait of height in human beings; often occurs when a trait is determined by more than one gene.

A

continuous variation

93
Q

A trait that is determined by the effects of more than one gene; such a trait usually exhibits continuous variation rather than discrete either–or values.

A

quantitative traits

94
Q

An allele that has more than one effect on phenotype is said to be

A

pleiotropic

95
Q

when a single gene affects more than one trait

A

Pleiotropy

96
Q

Some genes have more than two_______________

A

alleles

97
Q

How many alleles does blood have?

A

3

A,O,B

98
Q

Describes a case in which two or more alleles of a gene do not display clear dominance. The phenotype of a heterozygote is intermediate between the homozygous forms. For example, crossing red-flowered with white-flowered four o’clocks yields pink heterozygotes.

A

incomplete dominance

99
Q

In __________________, the phenotype of the heterozygote is intermediate between the two homozygotes.

A

incomplete dominance

100
Q

Cross between Rr x Rr results

A

incomplete dominance

101
Q

Describes a case in which two or more alleles of a gene are each dominant to other alleles but not to each other. The phenotype of a heterozygote for codominant alleles exhibit characteristics of each of the homozygous forms. For example, in human blood types, a cross between an AA individual and a BB individual yields AB individuals.

A

codominance

102
Q

neither allele is recessive and exhibits phenotype of both traits

A

codominance

103
Q

The gene that determines ABO blood types encodes an enzyme that adds

A

The gene that determines ABO blood types encodes an enzyme that adds

104
Q

The gene that encodes the enzyme, designated ___, has three common alleles: __, whose product adds galactosamine; ___, whose product adds galactose; and ____, which codes for a protein that does not add a sugar.

A

I
IA
IB
i

105
Q

IA and IB alleles are ________________

A

codominant (dominant over the i)

IA and IB alleles lead to sugar addition, whereas the i allele does not.

i is recessive (O-blood type)

106
Q

_____ and _____ alleles lead to sugar addition, whereas the i allele does not.

A

IA; IB

107
Q

Type A individuals add only galactosamine

A

IAIA homozygotes or IAi heterozygotes (two genotypes).

108
Q

Recieve A and O

Donatae A and AB

A

IAIA homozygotes or IAi heterozygotes (two genotypes).

109
Q

Type B individuals add only galactose

A

IBIB homozygotes or IBi heterozygotes (two genotypes).

110
Q

IBIB homozygotes or IBi heterozygotes (two genotypes).

Receive _____ and ______, Donates to ______ and ______

A

B
O
B
AB

111
Q

Type AB individuals add both sugars and are

A

IAIB heterozygotes (one genotype).

112
Q

Universal reciever, donates too _____

A

AB

113
Q

Type O individuals add neither sugar and are

A

ii homozygotes (one genotype).

114
Q

Universal donor, recieves ____

A

O

115
Q

The type of sugar attached to RBCs is dependent on the________________

A

allele that is expressed

116
Q

Sugar molecules are specific to an individual’s ________ system; recognizes ______

A

Immune

RBCs