Chapter 14 Flashcards
Toxicology
Study of nonfood substance taken by organism
forensic toxicology
how humans affected by drugs and poisons
pharmacology
science studies the relationship between drug on living things
pharmacokinetics
how drugs move into and out body
Absorption
passage of drug through tissue and into body stream
distribution
distributed locally by diffusion through tissues
metabolism
changed to a different from, metabolites
liver
elimination
excretion in urine
pharmacodynamics
how drugs act in the body
agonist
binds to receptor causes it to exert function
antagonists
drugs thay bind to receptors but don’t cause exert the action of the cell
Sampling
Urine, hair,
Liquid phase extraction
PH of drug dictates method of extraction
solid phase extraction
drugs selectively adapted onto wire and elites for further analysis
Enzyme multiplied immunoassay test
concentration
Radio immunoassay
radioactively labeled antigens for determine concentration
Confirmation test?
mass spectrometry
limit of detection
cut off level
level below which a result cannot be determined
level below which detection can’t happen
Widmark curve
plots blood alcohol concentration against time and reflect processes of absorption
BAC tests
gas chromatography
Preliminary breath testing instrument
infrared spectroscopy for measurement of alcohol
Field tests
horizontal gaze
walk and turn
touch nose
