Chapter 13 Regulation Of Gene Expression Flashcards

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0
Q

Gene regulation

A

Is the turning on and off of genes

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1
Q

Gene expression

A

Is the over process of information flow from genes to proteins

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2
Q

Why is that gene expression has to be regulated?

A

The control of gene expression allow cells to produce specific kinds of proteins when and where they are needed
Gene regulation can help organism respond to environmental changes

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3
Q

Almost all of the cells on the organism contain:

A

An identical genome

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4
Q

Only a _ of theses genes are used or expressed in each cell

A

Fraction

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5
Q

The difference between cells types are not due to the presence of different genes but instead due to selective gene expression

A

True

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6
Q

Differentiation

A

The normal process by which a less specialized cell develop or matures to the possess a more distinct form and function

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7
Q

Differentiation is controlled by turning specific sets of genes on or off

A

T

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8
Q

Levels of gene expression control

A
Chromatin structure 
Transcriptional structure 
Post transcriptional control 
Translational control 
Post translational control
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9
Q

Euchromatin

A

Loosely coiled DNA accessible to RNA polymerase

Transcriptionally active

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10
Q

Heterochromatin

A

Tightly packed DNA inaccessible to RNA polymerase

Transcriptionally inactive

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11
Q

DNA coiling and packing affect gene expression.

A

More tight packed less Likely to be transcribed

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12
Q

Barr body

A

An inactive X chromosome

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13
Q

Gene mutation

A

Is a permanent Change in the sequence of bases in DNA

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14
Q

Germ line mutation

A

Occurs in sex cells

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15
Q

Somatic mutation

A

Occurs in body cells

16
Q

Spontaneous mutations

A

Replication errors

DNA polymerase proofread

17
Q

Induced mutation

A

Cause by mutagens such as radiation and chemical

Many mutagens are also carcinogens ( cancer causing )

18
Q

Point mutation

A
Involves a change in a single DNA nucleotide 
Change one codon to a different codon  
Effect on protein vary 
Nonfunctional 
Reducing functionality 
Unaffected
19
Q

Frame shift mutation.

A

Nucleotides are either inserted or deleted from DNA

The protein is always a a different protein usually no function

20
Q

Silent mutation

A

No amino acids change no change in protein

21
Q

Missense mutation

A

Changes the amino acid producing a different proteins

22
Q

Nonsense mutation

A

Changes the amino acid into a stop codon producing short protein usually no function

23
Q

Proto-oncogenes

A

Stimulate cell division

24
Q

Tumor suppressor genes

A

Inhibit cell division