Chapter 12 (Psychopathology - Incomplete) Flashcards
hypofrontality hypothesis
The idea that schizophrenia may reflect underactivation of the frontal lobes.
dopamine hypothesis
The idea that schizophrenia results from either excessive levels of synaptic dopamine or excessive postsynaptic sensitivity to dopamine.
amphetamine psychosis
A delusional and psychotic state, closely resembling acute schizophrenia, that is brought on by repeated use of high doses of amphetamine.
chlorpromazine
An antipsychotic drug that replaced lobotomy as a treatment for schizophrenia.
clozapine
An atypical neuroleptic.
phencyclidine (PCP)
Also called “angel dust.” An anesthetic agent that is also a psychedelic drug. PCP makes many people feel dissociated from themselves and their environment.
psychotomimetic
A drug that induces a state resembling schizophrenia.
ketamine
A dissociative anesthetic drug, similar to PCP, that acts as an NMDA receptor antagonist.
glutamate hypothesis
The idea that schizophrenia may be caused, in part, by understimulation of glutamate receptors.
learned helplessness
A learning paradigm in which individuals are subjected to inescapable, unpleasant conditions.