Chapter 12 Nose and Smell Flashcards
Olfaction
the sense of smell
olfactory receptor cells
embedded in the nasal epithelium; dendrites branch into cilia containing olfactory receptor proteins
olfactory stem cells
cells with enough flexibility to differentiate into the various different types of olfactory receptor cells; allow the receptor cells to be regularly replaced, something that happens about everyone 1-2 months
Cilia
dendrites of olfactory receptor cells that branch out and are populated by olfactory receptor proteins
olfactory receptor proteins
GPCRs; humans have about 350 different olfactory GPCRs (on the low end); able to create a huge number of different scents because GPCR amplifes effect
Pseudogene
nonfunctional genes that, although appear to code for olfactory GPCRs, are altered in some way so that they do not code for functional receptor proteins; humans have about 600 of these
believed that humans lost function receptors through mutation because they were no longer needed; may serve some unknown regulatory function
essential oil
the oily concentrate of aromatic molecules from a plant; frequently includes many of a plant’s medicinal qualities
oily because the aroma-carrying molecules frequently are hydrophobic
often prepared by distillation, the process of heating an extract of the plant and concentrating the more volatile components
aroma
derived from the Greek word for “spice”
essential oil contains a complex mixture of chemical components (when smelling, humans are sniffing dozens of different molecules interacting with the 350 different types of olfactory receptors)
cinnamon
contains a highly aromatic essential oil, used to impart a distinctive flavor to both savory and sweet foods
cardamom
from India, seeds of this plant are used to impart a distinctive flavor to various Indian foods and to tea and coffee beverages
black pepper
fruit of another plant native to India, Piper nigrum; its aromatic essence is a mixture of numerous molecules; expensive due to popularity/high demand
sulfur, thiols
thiol refers to the sulfur-hydrogen (-SH) group; often smells stinky (i.d. skunks, asparagus pee)
specific anosmia
loss of sensitivity to a specific kind of smell (i.e. some people lack olfactory sensitivity to the asparagus-pee aroma)
general anosmia
loss of sensitivity to a large variety of aromas, in some vases even a complete lack of olfactory sensitivity; variety of causes ranging from nasal congestion to unknown developmental factors to head trauma to degenerative brain disease
hyperosmia
an increased sensitivity to odors; often appear transiently in association with a migraine headache or pregnancy