Chapter 12 Final Flashcards
A collapsed lung is also called:
Atelectasis
3 categories of atelectasis.
Resorption, Compression and Contraction
Resorption atelectasis most commonly results in:
Obstruction (MC in mucous in bronchus)
The type of atelectasis characterized by pleural effusion and common in CHF patients.
Compression atelectasis
The type of atelectasis characterized by fibrotic changes in the lungs.
Contraction atelectasis
Acute respiratory distress syndrome is characterized by:
Diffuse alveolar damage and prevention of gas exchange
Obstructive vs. Restrictive pulmonary diseases
Obstructive: Decreased expiratory flow rate
Restrictive: Decreased forced vital capacity
Permanent destruction and enlargement of pulmonary parenchyma (no fibrosis) are characteristics of:
Emphysema
What are the main subtypes of emphysema?
Centracinar and panacinar
The most common type of emphysema is:
Centriacinar
Centriacinar emphysema is characterized by:
MC in lung apices, and chronic smokers
Which type of emphysema is most common in the lower lungs?
Panacinar
Panacinar emphysema occurs as a result of a deficiency in what?
alpha1-antitrypsin
What is the difference in acini in both types of emphysema?
Centriacinar: Only central acini affected
Panacinar: Acini are uniformly affected
“Pink puffer” is characteristic of:
Emphysema
What is the hallmark of chronic bronchitis?
Hypersecretion of mucus
Chronic bronchitis is most common in what patient population?
Males (smokers)
“Blue bloater” is characteristic of:
Chronic bronchitis
Chronic bronchitis is defined as pronounced and productive coughing over _____ consecutive months in _____ consecutive years.
3 months over 2 years
The 4th leading cause of death in the US?
COPD
What is the difference between chronic bronchitis and asthma?
CB is irreversible, asthma is reversible
What percent of the US population has asthma?
10%
The most common type of asthma, also called genetic asthma.
Atopic asthma
Which type of asthma occurs with a family history, associated with skin reactions and has a childhood onset?
Atopic asthma
The type of asthma that has no allergen sensitization and is also called intrinsic asthma.
Non-atopic asthma
Emphysema causes:
Destruction of alveolar walls
The lethal form of asthma is called:
Status asthmaticus
Permanent dilation of the bronchial tree, necrotizing infections and foul/purulent sputum are all characteristics of:
Bronchiectasis
“Honeycomb lung” and “ground glass shadows” are signs of:
Chronic interstitial lung diseases
Diffuse interstitial fibrosis occurs most commonly in which patients?
Males > 60 years old
Nonproductive cough, dyspnea and “velcro-like” cracking on inspiration are all characteristics of:
Diffuse interstitial fibrosis
Pneumoconiosis results from:
Inhalation of particulates (workplace exposure MC)
Which types of mineral dust are inhaled in pneumoconiosis?
Coal dust, silica (MC) and asbestos
Coal dust vs. silica vs. asbestos inhalation
CD: No increase in lung cancer
Silica: Lung CA risk
Asbestos: Mesothelioma
The most common occupational disease worldwide is:
Silicosis (MC quartz)
Silicosis most commonly affects which lobes of the lung?
Upper lobes
What disease is most commonly going to manifest with noncaseating granulomas and bilateral hilar lymphadenopathy?
Sarcoidosis
Sarcoidosis is most common in younger adults of which descent?
African American
What is the classic triad of diffuse alveolar hemorrhage syndrome?
Hemoptysis, anemia and diffuse pulmonary edema
The classic form of DAHS.
Goodpasture syndrome
Wegener’s granulomatosis vs. Goodpasture syndrome.
Wegener’s: Type IV hypersensitivity, granulomas, males ~40 years
GPS: Type II HS, pulmonary infiltrates, DAHS, Males ~20-30 years/Females ~60-70 years old
Mechanisms of lung abscess.
Aspiration, obstruction and hematogenous
Lung abscesses occur MC on which side?
Right side
Chronic pneumonia manifests as which type of necrosis?
Caseous necrosis
Chronic pneumonia is caused by which microorganism?
Mycobacterium TB
Infection caused by TB is what type of hypersensitivity?
Type IV
What is the test given for TB?
Tuberculin (Mantoux) test
Which type of TB is asymptomatic and doesn’t transmit?
Primary TB
Which type of TB is associated with granuloma formation with possible cavitations?
Secondary TB
Which type of TB is MC with immunosuppression (HIV)?
Systemic miliary TB
The MC form of extrapulmonary TB is called:
Lymphadenitis
Which type of TB has a poor prognosis?
Secondary TB
Erythema nodosum is an inflammation of the fat cells just beneath the skin and is found in about 25% of patients with:
Sarcoidosis
Histoplasmosis is a _____ infection of the lungs involving inhalation of soil that is contaminated with bird and bat droppings.
Fungal
Primary lung CA is common and lethal. What does it MC affect?
Bronchial epithelium
Benign lung tumors that involve cartilage and vessels.
Hamartomas
The most common cause of CA-related deaths.
Pulmonary carcinomas
Pulmonary carcinomas account for ___% of lung CA dx and are most common in which population?
90%; 50-70 years old (smokers)
True/False: SCLC offers better prognosis than NSCLC.
FALSE; NSCLC offers a better prognosis than SCLC
Which type of pleural lesion is MC and is associated with pleural effusion?
Secondary
Hemothorax vs. Chylothorax
Hemo: Blood is in the pleural cavity
Chylo: Lymphatic fluid is in the pleural cavity
The MC type of pleural effusion, associated with CHF and hydrothorax.
Pleural transudate
Which type of pleural effusion is associated with pleuritis and is protein-rich?
Pleural exudate
Which pneumothorax is idiopathic?
Spontaneous
Which type of pneumothorax shifts the mediastinum and is a medical emergency?
Tension pneumothorax
What is the latency period after exposure for malignant mesothelioma?
25-40 years
The “common cold” is a type of:
Acute respiratory infection
The most common cause of acute respiratory infections.
Streptococcal pharyngitis (caused by Group A b-hemolytic streptococci)
Streptococcal pharyngitis may develop into:
Peritonsillar abscess or acute rheumatic fever
Infectious mononucleosis is caused by which microbe?
Epstein-Barr virus (EBV)
Two rare forms of laryngitis.
Tuberculous (chronic active TB) and Diphtheritic
Diphtheria is caused by which microbe?
Corynebacterium diphtheriae
Diphtheria is characterized by a:
“Dirty gray” pseudomembrane
Dangers of diphtheria?
Aspiration or airway obstruction and absorption of exotoxins
Laryngotracheobronchitis is also called:
Croup
Croup is caused by which microbes?
Parainfluenza virus and RSV
A “seal-like” bark is characteristic of:
Croup
Which laryngeal tumors are benign?
Vocal cord polyp and laryngeal papilloma or squamous cell papilloma
Laryngeal papillomas are caused by which virus?
HPV 6 and HPV 11
Throat cancer is an example of which type of laryngeal tumor?
Squamous cell carcinoma (95% of all cases)
How many cases of throat cancer are fatal?
1/3