Chapter 10 Final Flashcards
The #1 cause of death in the US is:
Heart disease
The most common mechanism of cardiac pathology.
Pump failure
Mechanisms of cardiac pathology.
Pump failure, obstruction of flow, regurgitant flow, shunted flow, dysfunctional cardiac conduction and rupture of heart wall/vessels
The common end-point for many cardiac diagnoses is that:
Heart cannot supply tissue demand
3 types of dysfunction in CHF.
Systolic, diastolic and valvular dysfunction
Systolic dysfunction is characterized by _____, and its risks are:
Loss of myocardial contractility; IHD and HTN
Diastolic dysfunction is characterized by ____ and its risks are:
Normal contraction but abnormal relaxation/filling; Female/older adults, left ventricular hypertrophy and fibrosis
Risks for valvular dysfunction.
Endocarditis, stenosis and HTN
Forward failure results in _____, while backward failure results in _____.
Hypoxia/insufficient output; Venous congestion
Adaptation that uses stronger contraction at the cost of oxygen.
Frank-Starling mechanism
Neurohumoral mechanisms use _____ to increase HR and _____ to cause vasodilation (balance).
Norepinephrine; ANP
Which mechanism results in overload and an increase in oxygen?
Cardiac hypertrophy
Left-sided heart failure is characterized by ______ and may cause ______.
Left ventricular hypertrophy and dilation; Pulmonary edema
What commonly results from left-sided heart failure?
Right-sided heart failure
Left-sided HF causes _____, while right-sided HF causes _____.
Pulmonary edema; peripheral edema
What percentage of congenital heart disease cases are idiopathic?
90%
CHD can be genetic and result from trisomies of which chromosomes?
13, 15, 18 and 21
What is the most common defect in CHD cases?
Ventricular septal defect (42%)
The second most common defect in CHD cases is:
Atrial septal defect (10%)
The most common shunt of CHD is:
Left-to-right shunts
Which shunt is characterized by cyanosis and tetralogy of Fallot?
Right-to-left shunt
What are the four characteristics of Tetralogy of Fallot?
VSD, right ventricular outflow obstruction, overriding of VSD by aorta and right ventricular hypertrophy
The most common CHD to cause cyanosis is:
Tetralogy of Fallot
In transposition of vessels, the right ventricle will connect to the:
Aorta
In transposition of vessels, the left ventricle will connect to the:
Pulmonary artery
Aortic coarctation is most common in _____ and those with which disease?
Males; Turner syndrome
Infantile aortic coarctation occurs where?
Proximal to PDA
Adult aortic coarctation occurs where?
Ligamentum arteriosum
90% of IHD cases result from:
Atherosclerosis (CAD)
Occlusion of the coronary arteries that may result in catastrophic consequences is termed:
Acute coronary syndrome
What percentage of occlusion is classified as critical stenosis?
> 70% occlusion
What percentage occlusion is likely to cause unstable angina?
90%
Sub-sternal chest pain, “crushing” or “squeezing” pain is the result of:
Angina pectoris