Chapter 12 - DNA: The Carrier of Genetic Information Flashcards

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1
Q

Helicase

A

opens the double helix at replication forks by disrupting the hydrogen bonds that hold the two strands together

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2
Q

single-strand binding protein (SSB)

A

binds to single strands of DNA and prevents the helix from re-forming before it can be used as a template for repliation

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3
Q

topoisomerase

A

breaks one or both DNA strand, preventing excessive coiling during replication, and then rejoins them in a more relaxed configuration

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4
Q

DNA polymerase

A

links nucleotide subunits to form a new DNA stand from a DNA template

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5
Q

DNA primase

A

synthesizes short RNA primers on the lagging stand, begins replication of the leading strand

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6
Q

DNA ligase

A

links okazaki fragments by joing the 3’ end of the new DNA fragment to the 5’ end of the adjoining DNA

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