Chapter 12 - DNA: The Carrier of Genetic Information Flashcards
Helicase
opens the double helix at replication forks by disrupting the hydrogen bonds that hold the two strands together
single-strand binding protein (SSB)
binds to single strands of DNA and prevents the helix from re-forming before it can be used as a template for repliation
topoisomerase
breaks one or both DNA strand, preventing excessive coiling during replication, and then rejoins them in a more relaxed configuration
DNA polymerase
links nucleotide subunits to form a new DNA stand from a DNA template
DNA primase
synthesizes short RNA primers on the lagging stand, begins replication of the leading strand
DNA ligase
links okazaki fragments by joing the 3’ end of the new DNA fragment to the 5’ end of the adjoining DNA